Biological Engineering

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From Biochemical Engineering to Synthetic Biology: A Short History of Engineering Impacts on Biotechnology

SBE Webinar

Sep 27, 2012

Harvey Blanch

This webinar will focus on how biochemical engineering developed in response to the need for large-scale production of antibiotics in the 1940s and 50s, even though fermentation provided a route to many industrial organic chemicals prior to their production from petroleum.

Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Food, Pharmaceutical & Bioengineering Division (FP & BE)

The FP&BE division coordinates AIChE's activities in the fields of food, pharmaceuticals, and bioengineering.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

Separate Processing of Hemicellulose and Cellulose to Optimize Ethanol Production From Corn Stover

Oct 17, 2011

Alexandre Chapeaux

Separate processing of hemicellulose and cellulose to optimize ethanol production from corn stover Alexandre Chapeaux, Nancy Dowe, Daniel J. Schell Using a series of thermochemical (pretreatment) and biochemical steps, lignocellulosic biomass is converted to sugars that subsequently can be made...

Energy Optimization of Hydrogen Production From Biomass

Oct 17, 2011

Mariano Martín

Energy optimization of Hydrogen production from biomass Mariano Martín a,b , Ignacio E. Grossmann b [1] mariano.m3@usal.es ; grossmann@cmu.edu a Departamento de Ingeniería Química yTextil. Universidad de Salamanca. Plz. Caidos 1-5 37008, Salamanca (Spain) b Department of Chemical Engineering...

Improved Ethanol Production Through Anaerobic Thermophilic Co-Culture From Various Carbohydrates

Oct 17, 2011

Lei Xu

Saccharification of fermentable sugars is one of the most critical steps in producing bio-ethanol from lignocellulosics through Consolidate Bioprocessing (CBP). However, the extreme pH and ethanol concentration are commonly considered to be the potential inhibitory factors for the application of...

Coupled Optimization and Simulation for Multi-Biomass Source-to-Biorefinery Supply Chain Modeling and Analysis

Oct 17, 2011

William Faulkner

As cost associated with fossil fuels rise due to various environmental, social, and economic factors, it has become prudent to examine the possibility of exploiting alternative sources of raw materials for the production of energy and chemicals. Biomass, of various forms, has been proposed as an...

A Model-Centric Solution to Link Content Uniformity Targets with API Particle Size Specifications and Process for a QbD Excercise

Oct 17, 2011

Salvador García-Muñoz

One of the contributing factors in determining targets for the particle size of an API can be the content uniformity of the dosage forms. This work presents a framework established with a model-based specification for particle size of the API that can be used in a bi-directional mode to: a)...

Ionic Liquid Pretreatment of Wood Biomass Leading to Enhanced Enzymatic Delignification

Oct 17, 2011

Muhammad Moniruzzaman

The biological pretreatment of wood biomass for degrading lignin, a complex aromatic polymer, has received much attention as an environmentally safe or “green” process. Generally, enzymes isolated from naturally occurring fungi, or with enzymes produced by genetically engineered fungi have been...

Improving the Sustainability of Biofuels Through Modification of the Biomass Production Subsystem: Application to Corn and Lignocellulosic Ethanol

Oct 17, 2011

Robert A. Urban

Concerns about dwindling fossil fuel reserves and climate change, energy independence, and depletion of ecosystem goods and services have driven the development of alternative technologies such as biomass-based fuels (biofuels). Although biofuels may be a step towards alleviating the aforementioned...

Modeling and Scale up of CO2-Water Pretreatment of Guayule Biomass

Oct 17, 2011

Ehsan Moharreri

A carbon dioxide – water pretreatment process was developed for guayule biomass. The guayule biomass was mixed with water and then loaded to a reactor where it was exposed to a biphasic environment consisting of CO2 rich vapor phase and water rich liquid phase. Then, the biomass was enzymatically...

Progress In Quality by Design Implementation In Fda's Office of New Drug Quality Assessment

Oct 17, 2011

Christine Moore

Since the launch of the Office of New Drug Quality Assessment (ONDQA) CMC pilot program in July 2005, over 40 Quality by Design (QbD) containing applications have been submitted, reviewed, and approved by ONDQA, both within and outside of the pilot. Although challenges still remain, many approaches...

The Influence of Nickel Phosphide On the Fractional Catalytic Pyrolysis of Hybrid Poplar Wood

Oct 17, 2011

Foster Agblevor

The pyrolytic conversion of biomass to into liquid fuels has the potential to become drop-in transportation fuels if some of its negative attributes such as high total acid number (TAN), high viscosity, and poor storage stability are overcome. We investigated nickel phosphide supported on fluid...

Catalytic Study On Lignin Degradation and Conversion Into Biofuels

Oct 17, 2011

Yulin Deng

Catalytic study on lignin degradation and conversion into biofuels Wei Mu and Yulin Deng School of Chemical and Biomolecular Engineering and IPST at GT, Georgia Institute of Technology, Atlanta, Georgia 30332-0620 Author for correspondence (e-mail: yulin.deng@chbe.gatech.edu ) As an ideal...

Fischer Tropsch Synthesis Via Biomass Derived Synthesis Gas

Oct 17, 2011

Syed Ali Gardezi

Due to the recent surge in energy costs and uncertainties in fuel prices, there is significant interest in seeking alternative sources of energy particularly from renewable such as biomass. Indirect liquefaction of biomass (via the thermo-chemical conversion to syngas followed by liquefaction via...

Biodegradation of Hardwood Lignocellulosics by the Western Poplar Clearwing Borer, Paranthrene Robiniae (Hy. Edwards)

Oct 17, 2011

Jing Ke

Plant lignin is a source of useful chemicals, and also the major barrier for saccharification of lignocellulosic biomass for ethanol conversion. The enzymatic lignin degradation/modification could bypass the need for chemical pretreatment and thereby facilitate bioprocess consolidation. Herein, we...

Effects of Mixing Quality On the Kinetics of Biomass Liquefaction

Oct 17, 2011

David M. Lavenson

Abstract: Biochemical conversion is a promising route to produce fuels and chemicals from cellulosic biomass. A key step in the process is biomass liquefaction, where enzymes are used to break down pretreated cellulosic particles. During this process, drastic changes in the mechanical properties of...

Effect of Transition Metal Catalyst On Lignin Oxidation During Alkaline Hydrogen Peroxide Pretreatment

Oct 17, 2011

Zhenglun Li

Biomass lignocellulose can be used as feedstock for bioethanol production, and a pretreatment is necessary for achieving high ethanol yield and economical feasibility. As a method to increase enzyme digestibility of biomass by selective delignification, alkaline hydrogen peroxide (AHP) pretreatment...

A QbD Approach to Improve Tablet Coating Uniformity

Oct 17, 2011

Atul Dubey

A combination of analytical and statistical methods is used to improve a tablet coating process guided by quality by design principles. A solid dosage form product was found to intermittently exhibit bad taste. A suspected cause was the variability in coating thickness which could lead to the...

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