Biological Engineering

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Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

Using Genomic Tools to Improve the Production of Biologics

November
2009
SBE Special Section
Dr. Wei-Shou Hu, Nitya M. Jacob, Wei-Shou Hu, Bernard Liat Wen Loo, and Miranda Yap
Recombinant DNA technology transforms mammalian cells into factories for protein-based therapeutics. New techniques provide chemical engineers with a better understanding of the process as well as the cells themselves.

SBE Special Section - Industrial Biotechnology

October
2005
SBE Special Section
June Wispelwey
Student Chapters Have Arrived! SBE Frontier Tutorial Second Bioengineering and Nanotech Conference Michael Shuler Wins Inaugural James E. Bailey Award Fishing Out Unusual DNA Enzyme is Linked to Neurological Disease

Algal Biofuels: The Research

March
2011
SBE Special Section
Kuan-Chen Cheng, Kimberly Ogden
The individual technical elements of the algae-to-biofuels process have already been demonstrated at the laboratory scale. Ongoing research seeks to refine the technology to enable scaleup to commercial production.

Recombinant Protein Therapeutics from CHO Cells -- 20 Years and Counting

October
2007
SBE Special Section
Dr. Wei-Shou Hu, Karthik P. Jayapal, Katie F Wlaschin, Wei-Shou Hu and Miranda G. S. Yap
The CHO cell is at its height of technological prominence thanks to its adaptability to various culture conditions and plasticity in the context of genetic alterations. With further research, the application ofCell Culture Strategies based on...

SBE Special Section: Biopharmaceuticals (Full 19-Page Supplement)

December
2015
SBE Special Section
Chun Chen, Chetan T. Goudar, Huong Le, Todd Przybycien, Nigel Titchener-Hooker
SBE Update: Continuous Progress in Biopharmaceuticals; Continuous Processing in Upstream Operations; Continuous Processing in Downstream Operations; A Look at the Regulations

Synthetic Biology: Putting Together the Pieces

July
2015
On The Horizon
Michelle Bryner
Synthetic biology represents a new way of building biological systems via engineering tools and principles. Genetic components and pathways will be created to reprogram organisms, endowing them with novel functions for a wide range of applications.

New Bandage Glows in Presence of Infection

December 22, 2015
British researchers have created a bandage that warns of common infections by turning a fluorescent green within four hours of pathogen detection. While a bandage often helps to...

New Products: December 2015

December
2015
New Products
Instrumentation Temperature Transmitters Feature Dual Sensor Inputs The THZ 3 and TDZ 3 two-wire (loop-powered) temperature transmitters provide an isolated and linear 4–20-mA output proportional to input. They can be configured quickly and easily...

The Blood-Brain Barrier and Drug Delivery

March
2013
SBE Special Section
William Olbricht
To maintain favorable conditions in the brain, the blood-brain barrier limits mass transfer across brain tissue. However, it also restricts the systemic delivery of compounds to treat neurological disorders. Several treatment alternatives to bypass...

SBE Special Section: Lignocellulosic Biofuels - Full 32-Page Supplement

March
2015
SBE Special Section
Tristan R. Brown, Robert Brown, Sergio C. Capareda, Bruce E. Dale, David Edwards, Vonnie Estes, Cesar Granda, Mark Holtzapple, Sagar Lonkar, Darlene Schuster, Charles Wyman
SBE Update; The Need for Biofuels; Producing Biofuels via the Thermochemical Platform; Producing Biofuels via the Sugar Platform; Producing Biofuels via the Carboxylate Platform; Scaling Up Bioenergy Technologies; Commercial-Scale Production of Lignocellulosic Biofuels

SBE Update: The Merging of Bio and Nano

December
2012
SBE Special Section
June Wispelwey
Earlier this year, the Society for Biological Engineering (SBE) organized its Sixth International Conference on Bioengineering and Nanotechnology (ICBN), which focused on bio-nanoscience and bioengineering for translational medicine. The conference...

Bioactive Devices: Uniting Form with Function

March
2013
SBE Special Section
Sujata Bhatia
Bioactive implants that combine a medical device with one or more biologic therapeutic agents show promise for the targeted treatment of complex medical conditions. Implantable medical devices, such as stents, grafts, and joint replacements, are...

Bio-Based Materials in the New Bio Economy

May
2012
SBE Special Section
Manjusri Misra, Amar Mohanty, Murali M. Reddy
Biological feedstocks are expected to gradually replace some fossil-based raw materials to create eco-friendly products, from car parts and packaging materials to electronic devices and other consumer goods - laying the foundation for a reduced-carbon economy.

SBE Special Section: Biopharmaceuticals - Continuous Processing in Upstream Operations

December
2015
SBE Special Section
Chun Chen, Chetan T. Goudar, Huong Le
Perfusion technology offers many benefits over fed-batch processing, such as reducing the size of the bioreactor, which reduces capital costs and enables the use of single-use bioreactor technology. Despite these advantages, a shift to continuous perfusion will likely be gradual.

Producing Fuels and Chemicals from Lignocellulosic Biomass

August
2008
SBE Special Section
Mark Holtzapple, Rocio Sierra, Aaron Smith, Cesar Granda and Mark T. Holtzapple
As oil and natural gas prices rise, lignocellulosic biomass becomes a viable feedstock for the fuel and chemical industries— provided key issues are addressed.

A MagDot-Nanoconveyor Assay Detects and Isolates Molecular Biomarkers

December
2012
SBE Special Section
Jeffrey Chalmers, Maryam B. Lustberg, M.D., Kalpesh Mahajan, Brandon Miller, Gang Ruan, Ratnasingham Sooryakumar, Gregory B. Vieira, Jessica Winter
The ability to quickly analyze, separate, and manipulate multiple types of biomarkers from small sample volumes is a significant step toward personalized medicine.

SBE Special Section: Biopharmaceuticals - SBE Update: Continuous Progress in Biopharmaceuticals

December
2015
SBE Special Section
Darlene Schuster
The goal of bioprocessing is to optimize natural or artificial biological systems by manipulating prokaryotic and eukaryotic cells and their environment to produce biopharmaceutical products. A bioprocess is divided into upstream and downstream operations. Upstream processing encompasses the steps from preliminary unmodified cell line culture to the mature modified cell culture and harvest; downstream processing includes the separation and purification of the biologics from the mature activated cell culture. These operations have typically been performed as batch processes.

SBE Update: Drug Delivery and Chemical/Biological Engineering

March
2013
SBE Special Section
June Wispelwey
Although you might not associate drug delivery with chemical engineering, the principles of chemical engineering — such as mass and energy balances, transport phenomena, reaction kinetics, and particle technology — are intimately involved in drug...

Biotechnology for Chemical Engineers

eLearning (online) Course
What chemical engineers working in design, operations and other support functions need to know about biotechnology.

Applications in Drug Delivery and Tissue Engineering

February
2006
SBE Special Section
Ali Khademosseini, Robert Langer
Nanotechnology is an emerging field that could potentially make a major impact on human health. Nanomaterials promise to revolutionize medicine and are increasingly used in drug delivery or tissue engineering applications.

SBE Supplement: Biochemical Engineering - Cell-Free Bioprocessing

November
2013
SBE Special Section
James Swartz
The ability to exploit a cell’s contents and capabilities unimpeded by cell walls opens new opportunities for the field of biochemical engineering. Cell-free biology could become the basis for making products from hydrogen to cancer vaccines and more.

Engineered Protein Templates Synthesize Inorganic Nanomaterials

December
2012
SBE Special Section
Arunagirinathan Adhimoolam, Sarah Heilshorn, Kelly N. L. Huggins, Alia Schoen, David T. Schoen
This powerful biomimetic method is a fast, flexible way to produce a wide range of inorganic nanostructures from a single protein scaffold.

Bioseparation Basics

October
2014
Back To Basics
Roger G. Harrison
Bioseparations are critical to the field of biochemical engineering. Each bioseparation process must be tailored to separate, purify, or recover the desired bioproduct. This article gives an introductory overview of filtration and chromatography — two key bioseparation unit operations.

Biology as a Basis for Biochemical Engineering

July
2013
Back To Basics
Sujata Bhatia
Biochemical engineering demonstrates the versatility of the living cell as a miniature reactor. Living cells can be genetically engineered to produce specific proteins, tuned to manufacture novel enzymes, and optimized to guarantee genetic stability and consistent production of desired products.

SBE Special Section: Biopharmaceuticals - Continuous Processing in Downstream Operations

December
2015
SBE Special Section
Todd Przybycien, Professor Nigel Titchener-Hooker
The transition from batch to continuous downstream processing of biologics has been gradual, with some processes integrating continuous and batch operations. A fully continuous, commercial-scale downstream process has yet to be implemented. Find out why, as well as the current status of the technology.

Biomaterials for Stem Cell Tissue Engineering

Archived Webinar
Apr 5, 2011
Stem cells have become a promising cell source in the tissue engineering field. Intense studies have been focused at the cell and molecular biology...

Photo Highlights from 2015 Honors Ceremony

November 9, 2015
The 2015 Institute and Board of Directors’ Award winners were given at the Honors Ceremony at the Annual Meeting in Salt Lake City. These are among AIChE’s most prestigious awards...

On-Site Biological Graywater Treatment

Archived Webinar
Aug 1, 2012
An Appalachian State University research team, is innovating the field of biological water treatment by applying a proven technology to salon and spa...

Polymer Nanotubes that Resemble Nerve Structures

August 26, 2015
Researchers at Sandia National Laboratories have created linkages of polymer nanotubes that resemble the structure of a nerve and are capable of transmitting electrical impulses...

CEP: News Update

August
2015
News Update
Sponge-Like Catalyst Makes Bioplastic Cheaper and Greener; LED Combines Optoelectronic Powerhouses; New Water Splitter Produces Hydrogen; Algal Fuel Gets a Boost; and more.

2011 ICBE: Stephen Turner on SMRT Technology

January 26, 2011
Stephen Turner from Pacific Biosciences spoke as an invited speaker in the Biomolecular Probes as Diagnostic and Therapeutic Reagents Session. His company has developed single-...

Understanding Biotech Basics

August 9, 2011
Need to understand biofuels better? Thanks to an exhibit called Science in American Life at the National Museum of Natural History, you can. In this video, you'll meet four...

Tar Sands CO2 Emissions Could Feed Algae Biofuel

May 23, 2013
Canada is betting on carbon capture and storage (CCS) to reduce the environmental footprint associated with making fuel from oil sands, but one of the country's largest oil-sands...

Purdue University wins YCOSST P3 Award

May 8, 2014
Purdue's Biowall entry took home the prize, with an ingenious design that improves indoor air quality thanks, in part, to plants' ability to purify air.

First-Ever DNA Sequencing Reference Tool Released

May 26, 2015
The National Institute of Standards and Technology (NIST) has release the world’s first “yardstick” to help ensure the accuracy of human DNA sequencing. The new tool, known as...

Electric Fields Interrupt Cancer Cell Division

March 8, 2012
Surgery, chemotherapy, and radiation are the best known methods for treating cancer, but in this TEDTalk (see video at right), Bill Doyle discusses a new methodology: tumor...

CEP: News Update

July
2015
News Update
Inks from Silk Show Biomedical Promise; Activated Carbon Gets a Designer Label; Graphene Coating Promises to Improve Condenser Efficiency; Solar Materials Self-Assemble for Lengthy Energy Storage; and more.
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