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Pharmaceuticals (Chemicals & Materials)

Algae - The New Green Crude

South Texas Section Webinar
Mar 1, 2012
Barry Cohen

Algae provides one solution to help the US reduce its dependence on foreign oil and create new green jobs. Barry Cohen and Will Thurmond will discuss both the technology and the commercial framework for the New Green Crude.

Chemical Engineering in the Pharmaceutical Industry: R&D to Manufacturing

October, 2010
This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences...

Aerobic Fermenter Scale-up: Why Equal Mass Transfer Scale-up Doesn't Always Work

Nov 9, 2009
Julian B. Fasano
Transferring oxygen to the liquid is only one of several steps that must occur in an aerobic fermentation. After the oxygen is transferred to the liquid, the liquid must be thoroughly mixed throughout the vessel. Then the oxygen must diffuse through the cell wall before finally being metabolized...

Understand Flow Patterns in Glass-Lined Reactors

November
2004
Reactions and Separations
Christopher J. Ramsey, David S. Dickey, Keith E. Johnson , Kevin J. Bittorf
Physical modeling and computer simulation provide insights into the performance of a glass-lined reactor.

Designing a Facility for API Development

March
2006
Plant Design
Terrence Fay, Yasha Zelmanovich
Kilo labs are instrumental in scaling up the production of active pharmaceutical ingredients. This article discusses the critical factors that must be considered to design such a facility.

Streamlining the Validation Process

March
2007
Management
Robert Mackey, Tim Flanigan
Today, validation is no longer an afterthought for the design and construction of a new or renovated process or facility. It is, in fact, recognized as an integral part of the total project. Fully integrated services are now available to ensure a...

Properly Select Equipment for SIP Systems

August
2007
Fluids and Solids Handling
Tony George
Sterilization-in-place (SIP) systems are essential to the operation of many pharmaceutical and biotech facilities. This article reviews design considerations, selection criteria and performance expectations for control valves, regulators, isolation...

Selecting Agitator Seals for Bioprocessing Applications

January
2008
Fluids and Solids Handling
Gregory T. Benz, William Ho Liam Teng
Issues such as sterility, isolation and contamination must be considered when choosing seals for use in biotech and pharmaceutical processes. This overview describes common types of seals and offers guidance on selecting the appropriate seal for...

Rx for Pharma

March
2009
Critical Issues
Girish Malhotra, P.E.
Chemical engineers could hold the key that helps pharmaceutical companies — facing pressure to control rising drug prices and competition from generics — reduce their manufacturing costs.

SBE Update

July
2009
SBE Special Section
June Wispelwey
Improving Biopharmaceutical Development

Exploring New Paradigms for Bioprocessing

July
2009
SBE Special Section
Jonathan Monk
Disruptive technologies, such as disposable bioreactors, metabolic ?ux models, and glycoengineered yeast, could change the face — and pace — of biomanufacturing.

Using Automation to Produce Quality Pharmaceuticals

October
2011
Instrumentation
Joseph S. Alford, P.E.
Automation can pay large dividends in the form of reduced process cycle times, lower operational costs, and more-consistent processes for manufacturing high-quality pharmaceutical products.

An Introduction to Immunity and Vaccines

November
2011
SBE Special Section
Derek Lapiska
An understanding of the basic approach to creating vaccines, as well as how vaccines confer immunity, is essential to developing safe and cost-effective formulations.

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