2006

Fulfilling the Promise of Nanomedicine

February
2006
SBE Special Section
Cristina Roman Vas, Rita D'Aquino with Tim Harper
Leveraging nanotechnology in the life science industries has given scientists new tools with which they have the potential to transform the world of medicine.

Building Models from Simulator Runs

January
2006
Computational Methods
Aad van Veldhoven, Magali de Macedo
The design-of-experiments approach has the advantage of providing the framework to build complex models with minimum use of time and effort.

Designing a Facility for API Development

March
2006
Plant Design
Terrence Fay, Yasha Zelmanovich
Kilo labs are instrumental in scaling up the production of active pharmaceutical ingredients. This article discusses the critical factors that must be considered to design such a facility.

Mother Nature as both Doctor and Patient

November
2006
SBE Special Section
Edwin N. Lightfoot
Once we have grasped some essentials of this riotous, but surprisingly well ordered world, we shall find our transport phenomena background to have real utility.

Right-Sizing Environmental Controls

June
2006
Environmental Management
E. Joseph Duckett
Size does matter - and bigger is not necessarily better when it comes to pollution control. It is more important to be the right size than the largest size.

Industrial-Scale Flare Testing

May
2006
Environmental Management
Charles Baukal, Jianhui Hong, Mahmoud Fleifil, Robert Schwartz
Advanced flare testing at full scale can help to ensure that the system operates as designed. This article explains what's involved and the parameters that should be measured and evaluated to demonstrate performance, reliability and safety.

Simplify Wastewater Treatment Process Design

January
2006
Environmental Management
Apostolos Vlyssides, Elli Maria Barampouti, Sofia Mai
Unlike time-consuming conventional methods, this approach to designing a dissolved air flotation (DAF) plant requires only the physical characteristics of the flocs — their size and density, flowrate and temperature.

Avoid the Pitfalls of Bioprocess Development

August
2006
Process Development
Mukesh Doble
This article presents the challenges that an engineer might encounter when designing or scaling up bioprocesses and offers practical solutions, including those cited in literature.

Who Done It? The ABCs of Environmental Forensics

March
2006
Environmental Management
Jeffrey Bolin, Matthew Schroeder, Michael Sklash
These tools and techniques can be used to make sense of soil or groundwater contamination - where it came from, who is responsible for it, and how to fairly allocate the costs to clean it up.

Bioprocess Design for a Novel Vaccine

November
2006
SBE Special Section
Barry C. Buckland
The challenges of vaccine development are not limited to identification of suitable antigens, adjuvants and delivery methods, but include regulatory, technical and manufacturing hurdles in translating a vaccine candidate to the clinic.

Fundamentals of Effective Leadership

June
2006
Career Catalyst
Richard J. Kinsley
To become a leader people want to follow, focus on the team's objectives, avoid self-deception, build strong relationships, and enable others to achieve the team's goals.

Cancer's Newest Deadly Foe

February
2006
SBE Special Section
Suzanne A. Shelley
An array of nanoscale developments are poised to revolutionize cancer diagnosis and drug discovery efforts, and create new ways to target the delivery of potent, often toxic drug therapies, while reducing their dose-limiting side effects.

Reduce Business Risk with a CMS

October
2006
Environmental Management
Robert F. Boland
A compliance management system (CMS) helps companies meet regulatory reporting requirements, improve environmental performance, reduce environmental compliance costs, and increase organizational efficiency. Here's a run-down of what to look for when...

Match the Effort to the R&D Investment

January
2006
Career Catalyst
Kelly Ibsen
Using a phased engineering approach to guide R&D projects will improve efficiency and avoid costly experimental excursions.

Ionic Liquids for Aromatic Extraction: Are They Ready?

December
2006
Reactions and Separations
Sachin T. Anjan
Ionic liquids have already moved into the commercial arena as reaction solvents. This article compares them to conventional solvents and examines their potential for the extraction of benzene, toluene and xylene from reformate.

Get Your Investment Decisions Right

February
2006
Management
Gerald Bode, Gregory J. McRae, Konrad Hungerbuhler, Reinhard Schomacker
This article describes state-of-the-art investment analysis techniques, shows how and why even reasonably good analyses can lead to bad decisions, and gives guidance on how to avoid mistakes when making investment decisions regarding chemical...

Optimizing the Asset Management of Pumps

May
2006
Asset Management
Deane Horn, Mark Granger
Integrating new advances in smart online pump monitoring and flexible communication technologies can improve pump reliability and performance while reducingcosts.
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