Fundamentals of Protein Degradation and Stabilization

Protein degradation occurs throughout the life cycle of biotechnology products, and can involve a variety of physical and chemical routes. This session seeks contributions that focus at a fundamental level on the mechanism(s), kinetics, and/or quantitative modeling of one or more degradation pathways for proteins in vitro or in vivo. These may include, but are not limited to: deamidation, oxidation, proteolysis, and non-native aggregation. Priority will be given to those contributions that provide insights or applications of general use, and those that apply modern computational or theoretical tools.