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Pharmaceutical and specialty chemicals opening (4/21/15)
Hoecker and Kohl partners with top employers located throughout the country on engineering opportunities in the areas of chemical process and controls design. This client is local in the St. Louis area and is experiencing a sustained period of tremendous growth. The below is a sampling of the responsibilities and qualifications for this position and are not intended to be all inclusive.
- Preparation of documentation (batch records, charge sheets, spec sheets, hazard sheets, PSORs, air emissions, processing reports) necessary to support processing in the plant
- First time scale-up and/or preparation of materials in the pilot plant based on defined process chemistry
- Knowledgeable in ICH Q7 guidelines for the preparation of bulk API for clinical use
- Competency in organic chemistry at the level necessary to facilitate implementation of development processes into commercial like process equipment
Education and Experience:
- Bachelor of Science Degree in Chemical Engineering with 3+ years of experience in scale¬ up/preparation of pharmaceutical and specialty chemicals
This is an immediate need with a dynamic organization offering a consultative and collaborative environment of critical thinkers. For more details about both this client and opportunity please call (314) 735-0800, send an email to firstname.lastname@example.org or visit the website at www.hoecker-kohl.com.
Short-Term Development Project in St. Louis (2/27/15)
The successful applicant will support the development of chemical and biochemical processes and technologies for bio-conjugate- and polytide-derived biotherapeutics. The position will focus on process engineering, unit operation scale-up and scale-down and apply rigorous and engineering principals and approaches to all aspects of conjugate process development and equipment design. This is a full time engagement (40 hours/week), starting in March 2015 and estimated to continue through September, 2015. Work must be performed at the client’s location in the St. Louis area.
To be considered for this opportunity, the candidate should have the following skills and characteristics:
- Minimum BS in Chemical/Biochemical Engineering or equivalent or related field with 0-5 years industry experience.
- 2-3 years of process development of bio-therapeutics desired.
- Experience in developing relevant purification processes for complex biologics
- Good understanding of chemical/biochemical engineering and macromolecule analytics.
- Familiarity with recent scientific literature required.
- Strong analytical and computer skills essential.
- Strong oral and written communication skills.
- Experience in laboratory automation and LabView software is desired.
- Minimum of 1-3 years of GLP experience
Primary responsibilities for this role include:
- Work with fellow scientists to design and execute experiments including small-scale studies, and pilot plant and manufacturing studies in a variety of types and scales of equipment from bench top to pilot-scale.
- As required, complete technology transfer and validation in commercial plants.
- Based on analyses of the studies, develop and test new hypotheses to improve fundamental understanding of the chemical and biochemical processes, including bio-conjugation or large and small molecule combinations.
- Support process validation, quality by design, regulatory approaches, and quality systems
- Collaborate with the pilot plan and manufacturing staff on experimental studies, clinical manufacturing, and process validation, including work with external contract manufacturing organizations.
Interested candidates will also need to visit our website so that they may enroll in our network. Information about enrolling as an expert and the YourEncore project process is available in our Expert Guide at http://www.yourencore.com/expertguide.
If interested in being considered for this opportunity, please contact the following: