Kaiyi is an assistant professor in Princeton University's Omenn-Darling Bioengineering Institute. Previously, he completed his Ph.D. in Biological Engineering at MIT, where he developed technologies in RNA-guided systems, protein engineering, and synthetic biology under the guidance of Drs. Omar Abudayyeh and Jonathan Gootenberg. After his PhD, Kaiyi joined Amgen as the Inaugural Amgen Science Fellow under the mentorship of Dr. Howard Chang, where he leads a group in using deep learning and synthetic biology approaches to design novel therapeutics. Kaiyi's research has been recognized by awards including MIT Technology Review Innovator Under 35 list, 30 under 30 award, and Wishnok Prize from MIT. Kaiyi's group at Princeton combines synthetic biology and generative AI to program macromolecules and cells to understand molecular circuit behind disease and homeostasis. With this knowledge, the group develops technology to engineer better therapeutics to address diseases including cancer, autoimmune disorders, and aging.