In This issue
CAREER CATALYST
Disarming the Firing Squad
If thoughts of a layoff keep you up at night, stop wringing your hands and start taking action. Follow this 11-step plan to position yourself for success in these uncertain economic times.
Kate Wendleton
SAFETY
Managing Security Risks
Process hazard analysis techniques can be modified to address plant security through a security vulnerability analysis.
Donald W. Abrahamson and Adrian L. Sepeda
FLUIDS AND SOLIDS HANDLING
Reshaping the Structure of Fluidized Beds
Adding structure to a gas-solid fluidized-bed reactor changes the system’s hydrodynamics and can improve performance.
J. Ruud van Ommen, John Nijenhuis, and Marc-Olivier Coppens
BACK TO BASICS
Understanding Sealing Solutions
The right seal can help a plant save money, eliminate leaks, and avoid safety problems. Here’s how to select and install gaskets for effective sealing.
Jim Drago and Matt Tones
SBE SPECIAL SECTION: DISPOSABLE EQUIPMENT
SBE Update
Improving Biopharmaceutical Development
June C. Wispelwey
Exploring New Paradigms for Bioprocessing
Disruptive technologies, such as disposable bioreactors, metabolic flux models, and glycoengineered yeast, could change the face — and pace — of biomanufacturing.
Jonathan Monk
The New Disposable Evolution
Single-use systems have advanced from a limited product line to several new products for a wider range of unit operations. As these technologies evolve, new size, cost, and regulatory needs continue to fuel industry growth.
Joanna Ziemlewski
Disposable vs. Traditional Equipment — A Facility-Wide View
This analysis shows how to quantify the capital and operating differences between single-use and reusable equipment for a model biopharmaceutical process.
Craig Sandstrom
Sponsored Links
Measuring Powder in Very Small Quantities
Batch-to-batch color consistency (whiteness, for some) is an important indicator of quality for many powders. The whiteness of powder may be an indication of its freshness or purity. Frequently only a small amount of powder may be available for measurement.
HunterLab
Environmentally friendly lead-free alternatives for Lindlar catalysts
BASF introduces the lead-free Pd-based catalysts NanoSelect™ LF 100 and LF 200. In contrast to the classical Lindlar catalyzed hydrogenation processes, these new heterogeneous catalysts provide a green, lead-free alternative. In addition, the reduced precious metal content of the catalysts results in significant process cost savings. Comparison of the performance of with Lindlar catalyst in selective hydrogenation reactions reveals similar activity and selectivity. More over, the observed activity for the NanoSelect catalysts is similar to the activity observed for Lindlar catalyst but obtained with a ten-fold lower metal content. Consequently, the overall process cost can be reduced dramatically due to the lower amount of precious metal in the reactor. Find out more today at www.nanoselect.catalysts.basf.com.
