Biochemical Processes

Tools for Engineering Non-Growth Metabolism

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2015 - 12:30pm-3:00pm
Stationary phase metabolism that is not carbon-limited is ideal for metabolic engineering. Without cell growth, feedstocks can be efficiently...

Bioreactor Design for Chemical Engineers

Back To Basics
Gregory T. Benz
Fermentation processes are based on chemical engineering principles. Understand these concepts to achieve optimal bioreactor design.

Intro to Maintenance and Reliability

Archived Webinar
Mar 11, 2015
This presentation provides those in the process and discrete manufacturing industries an introduction to the best practices in Maintenance and...

Single Use Centrifuge- CHO Clarification

Conference Presentation
AIChE Annual Meeting
Thursday, November 7, 2013 - 4:00pm-4:30pm
Abstract Text: The large scale economic collection of proteins is an important problem for the Biotechnology industry. Generally , proteins are...

Effect of Anti-Apoptosis Genes On Clarification Performance

Conference Presentation
AIChE Annual Meeting
Wednesday, November 6, 2013 - 3:45pm-4:00pm
Optimal bioreactor harvest time is typically determined based on maximizing product titer without compromising product quality. We suggest that ease...

On the Modeling of Oral Drug Delivery

Conference Presentation
AIChE Annual Meeting
Thursday, November 1, 2012 - 12:30pm-1:00pm
On the Modeling of Oral Drug Delivery Naresh Pavurala, Luke E.K Achenie Department of Chemical Engineering, Virginia Polytechnic Institute and State...

Piloting Bioreactors for Agitation Scale-Up

Reactions and Separations
Gregory T. Benz
This article offers guidance on how to design appropriate experiments to measure scalable data for agitation in both aerobic and anaerobic bioreactors.

Keys to Bioreactor Selection

Reactions and Separations
John A. Williams
A few basic types of bioreactor designs are used to produce a wide range of products, from antibiotics to foods to fuels. Here's how to pick the best options for your application.

Fermentation Goes Large-Scale

Special Section
Aristos Aristidou , J. J. Hahn , Pim van Hoek , Alex Patist
Designing an economically competitive and environmentally sustainable fermentation route means considering the downstream separations needed to capture the final product during the initial process design.

Clarifying Centrifuge Operation and Selection

Fluids and Solids Handling
Victor Norton ,  William Wilkie
Before selecting a centrifuge for your application, understand its principles of operation and investigate the key process variables.
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