2010

Nano Copper Oxide: From Flame Spray Pyrolysis to Photoelectrochemical Hydrogen Generation

Conference Presentation

AIChE Annual Meeting

Thursday, November 11, 2010 - 7:00pm

A systematic experimental study of the synthesis of copper oxide nanoparticles and nanoporous films is presented. Powders were made by flame spray...

Photoelectrochemical Properties of Birnessite-Type MnO2 Thin Films for Solar Water Splitting

Conference Presentation

AIChE Annual Meeting

Thursday, November 11, 2010 - 7:00pm

Photoelectrochemical (PEC) water splitting to produce clean hydrogen fuel is an attractive method for harvesting intermittent solar energy and...

Raman and XPS Investigation of Copper Promoted Transition Metal Doped Ferrites – High Temperature Water Gas Shift Activity

Conference Presentation

AIChE Annual Meeting

Thursday, November 11, 2010 - 7:00pm

In our previous studies, we introduced a variety of metal ions (M = Cr, Mn, Co, Ni, Cu, Zn, and Ce) into iron oxide (spinel lattice) and screened for...

Placement of Catalyst in Electrospun Silica Nanofibers for the Alkaline Hydrolysis of Biomass

Conference Presentation

AIChE Annual Meeting

Thursday, November 11, 2010 - 7:00pm

The use of electrospinning to generate one dimensional materials has garnered significant interest lately due to its inexpensive nature and the...

Impact of API Particle Size On a Sustained Release Oral Tablet Formulation

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

The objective of this study was to understand the impact of API particle size on various blend and tablet quality attributes of a sustained release...

Study of Mixotrophic and Photoheterotrophic Metabolisms in Cyanothece Sp. ATCC 51142 Via Isotopomer-Assisted Metabolite Analysis

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

The unicellular diazotrophic cyanobacterium, Cyanothece sp. ATCC 51142 (Cyanothece 51142), is able to grow aerobically in nitrogen-fixing conditions...

Mixture DOE and Design Space

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Present a case study on mixture DOE involving five components used to formulate a pharmaceutical tablet. The goal is to achieve a sustained release...

Lung Disease Diagnosis From Gene Expression Profiles

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Lung diseases include some of the most widespread and deadly conditions known to affect people in the US today. One of the main challenges in...

Can A Design Space Be Built On Material Attributes Alone?

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

In April, 2009, the PhRMA Drug Product Technical Group sponsored an industry workshop to explore the practicality and limitations of defining a...

Practical Application of Q8 and Q9 Principles in Pharmaceutical Development

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

The presentation “Practical application of Q8 and Q9 principles in pharmaceutical development” gives an overview of the current practice in...

Quality by Design Approach to Pharmacokinetic Modeling. A Case Study On Cyclosporin A

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Drug dose response experiments in animals provide invaluable information about the pharmacokinetics and pharmacodynamics of new therapeutic agents...

PVA-Calcium Oxide Composite Membrane for Direct Methanol Fuel Cell

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

The large scale utilization of Nafion® in Direct Methanol Fuel Cell( DMFC) is still constrained by high methanol permeability and high temperature...

A Framework for in-Silico Formulation Design and Optimization Using Multivariate Latent Variable Regression Methods

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Quality by Design is a technical exercise that should be performed upstream in the design of the production train for a given product. Although each...

An Integrated Quality-by-Design (QbD) Approach towards Design Space Definition of Key Unit Operations In the Manufacturing of Solid Dosage Forms by Discrete Element Method (DEM) and Computational Fluid Dynamics (CFD) Simulation

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Combined Quality-by-Design and computer simulation approaches (discrete element method and computational fluid dynamics) are presented to...

Stability and ORR Activity of Nitrogen Functionalized Ordered Mesoporous Carbon Supports

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

The most popular catalyst for low temperature proton exchange membrane fuel cells (PEMFC) is platinum (Pt) nanoparticles supported on carbon [1]. One...

Modelling and Informatics Challenges IN Film-BASED Drug Formulations and Manufacture

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Drug-loaded thin films are a novel pharmaceutical administration form that is creating an increasing interest in the pharmaceutical industry due to...

Achieving QM Accuracy at a Fraction of Computational Cost: Lattice Energy Minimization of Organic Crystals Containing Highly Flexible Molecules

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

There is a multitude of possible formulation pathways for pharmaceutical compounds among which polymorph, solvate, salt and cocrystal formation are...

Zeolite – Protic Ionic Liquid Composites: Preparation, Characterization and Evaluation of Ion Conduction Properties

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Fuel Cells (FCs) have been recognized as one important device for efficient transformation of chemical energy to electricity. Among the different FC...

Pragmatic Application of Crystallization Design Basics for a Pharmaceutical Compound

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

An API crystallization can be sufficiently developed to provide a robust process utilizing basic design principles and simplified modeling techniques...

Carbohydrate Circle and Genetic Information Flow Studies of Escherichia Coli Reveal the Molecular Mechanisms of Resistance to Balofloxacin

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Protein-protein interactions are pivotal in many biological processes and essential for a global understanding of cell functions. In the present...

Drop-On-Demand Dispensing of Pharmaceutical Suspensions: Correlation of Material Attributes and Operating Conditions to Process Performance

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

The ability to produce drops on demand is critical to microdosing applications, such as dispensing inks, polymers, and other biological fluids. In...

A Molecular Dynamics Simulation Study of Hydrated Sulfonated Poly (Ether Ether Ketone) for Application to Polymer Electrolyte Membrane Fuel Cells

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

S-PEEK has been known as one of the promising candidates for fuel cell application since it has high thermo-oxidative stability and extraordinary...

Computational Predictive Models Applied to Scale-up of Solid Oral Drug Products

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

The budget-restricted pharmaceutical environment is countered by the heightened expectations for drug products to be developed using science-based...

Short and Long-Term Changes in Circulatory Protein and Cytokine Profiles Following Burn and CLP Treatments

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Burns and trauma lead to a hypermetabolic state characterized by an accelerated breakdown of skeletal muscle protein in the patient which leads to...

Plantwide Dynamic Simulation and Model-Based Control of a Continuous Pharmaceutical Process

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

GENENTECH: A Rich History of Chemical Engineering Innovation

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Throughout its history, Genentech scientists and engineers pioneered and then exploited the use of recombinant DNA technology to develop and...

Spray Drying Process Design: Establishing Links Between Process Parameters and Product Performance

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

Spray drying or spray congealing is typically used to manufacture a powder for further processing into a final dosage form. Although this operation...

F-Test in k-Fold Cross Validation and Its Application to the Discovery of Biological Networks

Conference Presentation

AIChE Annual Meeting

Wednesday, November 10, 2010 - 7:00pm

There has been considerable emphasis in the recent years on applying systems approaches to decipher and reconstruct cellular networks using high-...