2007

Educational Perspective on the Future of Chemical Engineering

January
2007
Special Section
James T. Cobb Jr., Gary K. Patterson, S. Ranil Wickramasinghe
Diversification, globalization, emerging technologies...Times have certainly changed for chemical engineers. But, has the undergraduate chemical engineering curriculum kept pace?

Properly Select Equipment for SIP Systems

August
2007
Fluids and Solids Handling
Tony George
Sterilization-in-place (SIP) systems are essential to the operation of many pharmaceutical and biotech facilities. This article reviews design considerations, selection criteria and performance expectations for control valves, regulators, isolation...

Improving Heat Exchanger Designs

April
2007
Heat Transfer
Christopher A. Bennett, David C. King, R. Stanley Kistler, Thomas G. Lestina
This article defines and explains the factors that affect heat exchanger design margins. With the proper application of design margins, capital costs can be lowered and plant operations improved.

Scaling Fixed-Bed Catalyzed Processes

March
2007
Reactions and Separations
Jonathan H. Worstell
The new parameter introduced here will yield more meaningful results when a fixed-bed reactor is scaled up for process development or scaled down for plant support.

Selecting and Using Bolted Head Closures

April
2007
Fluids and Solids Handling
John C. Birkmire, P.E.
Proper design, fabrication, assembly and operation of a pressure vessel closure are essential to ensuring product containment, integrity and quality.

Bioprinting: Directed Tissue Self-Assembly

December
2007
SBE Special Section
Vladimir Kasyanov, Roger Markwald, Vladimir Mironov
Imagine eliminating patient waiting lists for organ transplants. Bioprinting holds the promise of making this happen, but, must research must be done first.

Effectively Manage the Lifecycle of a Product

July
2007
Information Technology
Baha Korkmaz, Marty Martin
By incorporating the batch standards S88 and S95 into the entire product lifecycle, companies can optimize their processes and project management. This enables them to rapidly get their products to market — a critical factor in staying competitive.

Modular Mini-Plants: A New Paradigm

March
2007
Management
Shashank Shah
Modular design principles are well known, but have found only niche applications in the Chemical industry. This article outlines an innovative methodology, whereby plant and process design may be conducted in parallel using components with pre-...

A Simple Approach to Vapor Pressure Prediction

January
2007
Reactions and Separations
Andrew J. DeDoes, Matthew D. Goetz, Michael J. Misovich
This method reproduces the vapor pressure predictions of the Soave-Redlich-Kwong and Peng-Robinson equation of state with a simple Antoine equation that uses constants derived from critical properties and the acentric factor.

Dividing-Wall Columns Find Greater Appeal

May
2007
News Feature
Gerald Parkinson
Conceived more than seven decades ago, dividing-wall columns are now only gaining widespread acceptance. The reasons— the drive to save energy and advances in computer technology that have overcome the burden of doing complex column internal designs.

The G-Value for Agitator Design: Time to Retire It?

March
2007
Fluids and Solids Handling
Gregory T. Benz
This commonly used number does not correctly address the influence of viscosity, and has no relationship to performance parameters such as fluid velocity and blend time. This article recommends actual measures of agitator performance that should be...

Deciphering the Mechanisms of Therapeutic Protein Production

October
2007
SBE Special Section
Daniel W. Allison, Christoph L. Bausch, Trissa Borgschulte, Matthew V. Caple, Kevin J. Kayser
Demand for therapeutic recombinant proteins will eventually exceed current production capabilities. This is a major driver in further understanding Chinese Hamster Ovary (CHO) cell biology, which is the cell line of choice for producing these...

Controlling Emissions During Cold Furnace Startup

February
2007
Environmental Management
Wes Bussman, Jianhui Hong, Charles E. Baukal Jr., Richard T. Waibel
High carbon monoxide emissions from a furnace while its temperature is being ramped up can exceed permit limits if appropriate measures are not taken. Here are a few suggestions.
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