(115d) Mini- and Micro-Scale Units in Process Development
AIChE Spring Meeting and Global Congress on Process Safety
2012
2012 Spring Meeting & 8th Global Congress on Process Safety
Process Development Division
Best Practices In Pilot Plant Development and Operation
Wednesday, April 4, 2012 - 9:30am to 10:00am
Overall societal and industry trends of accepting less risk and desiring a higher degree of safety assurance, has impacted R&D experimental practices. One approach to reducing risk while maintaining an ability to experiment (and learn) quickly, is to reduce the scale of experiments. Smaller scale experiments entail lower total energy and/or chemical hazards, by definition, than those conducted at a larger scale. Relevance to commercial scale-up requires more attention however to underlying fundamental phenomenon, in the absence of which the technical scale-up risk increases.
Approaches to scale-down of fixed-bed reactors, ion exchange and adsorption systems, crystallization, distillation, and other unit operations, will be examined via a number of case studies. Included are examples of semi-integration of the micro-scale units to comprise a pilot demonstration of concept. Use of multi-throughput or “side-by-side” experiments to overcome experimental error and offsets (including batch to continuous translations), will be demonstrated through examples.
Topics
Checkout
This paper has an Extended Abstract file available; you must purchase the conference proceedings to access it.
Do you already own this?
Log In for instructions on accessing this content.
Pricing
Individuals
AIChE Pro Members | $150.00 |
AIChE Graduate Student Members | Free |
AIChE Undergraduate Student Members | Free |
AIChE Explorer Members | $225.00 |
Non-Members | $225.00 |