(331a) Experiments and Simulations of Microbial Growth in a Rotating Bioreactor
Coupled with detailed experiments, we utilize Stokesian dynamics to accurately describe the suspension mechanics of microbes (spherical and aspherical) in a RWV. Using a spherical particle as a building block, we can construct any pseudoshape that we desire. For this work, we construct aspherical particles and the rotating wall so that the hydrodynamic interactions can be accurately calculated. Furthermore, we develop scaling arguments for the parameters that control the operating regime to direct efficient operation of RWV. These parameters consist of dimensionless groups that include the aspect ratio of the sizes of the microorganism and the bioreactor, the rotational velocity of the bioreactor, and the material properties of the suspending media.