(273h) Novel Method for the Integration of Flexibility and Stability in Design of Chemical Processes Under Parametric Uncertainties
The major difficulty of integrating flexibility and stability lies in how to convert the Lyapunov stability conditions into specific constraints embedded within the flexibility analysis model. This paper proposes a novel method for integrating flexibility with stability, which incorporates stability constraints obtained by singularity theory based stability analysis method into the MINLP model to calculate flexibility index. The singularity theory based stability analysis method can characterize regions in parameter space over which different kinds of stability characteristics may exist.
As a result, a stable flexible region is obtained, which not only adapts to variations in uncertain parameters, but also ensures stable operation and process inherent safety. 1,3-propanediol fermentation system and methyl methacrylate polymerization process have been studied to demonstrate the effectiveness of the proposed methodology. The obtained results illustrate that the novel method for considering flexibility and stability simultaneously possesses distinct computational advantages over the eigenvalue optimization algorithm, so it has great potential for applications in large-scale systems.
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 Jiang, H., Chen, B., Wang, H., Qiu, T., & Zhao, J. (2014). Novel method for considering process flexibility and stability simultaneously. Industrial & Engineering Chemistry Research, 53(38), 14765-14775.