(230s) Dynamics of Linear and Comb DNA Solutions Using Efficient Brownian Dynamics Techniques
To investigate the properties of DNA solutions using coarse-grained bead-spring chains, a new technique is developed on the basis of properties of exact worm-like chain (WLC). In this approach, the correct correlation along the chain is modeled through the introduction of a bending potential and the spring force-law is obtained using asymptotic behavior of WLC at small and large forces. Using this model, the relaxation and stretching dynamics of linear and comb DNA molecules are evaluated and compared against experimental data .
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