(631h) Effect of Composition and Temperature On the Structural Evolution and Dissolution Behavior of Drug/Polymer Systems
AIChE Annual Meeting
Wednesday, October 19, 2011 - 6:00pm to 8:00pm
In this study, it is found that both the composition and crystallization temperature played important roles in determining the size and location of the drug domains in the polymer matrix and hence affect the dissolution behavior. By optimizing the preparation parameters, the formulation with desired performance can be designed.