Mixing In Aerobic Fermentation Processes

In this presentation the general rules describing the selection of equipment configuration for gas-liquid reactions will be discussed and for selection of impeller operating conditions in an agitated vessel, particularly how the impeller type, diameter and operating speed are related to the gas flow rate and mass transfer requirements. The special considerations that must be taken into account when designing agitators for aerobic fermentations will be reviewed and finally, an example will be presented showing how the design calculations are applied to analysis of data from an existing pilot or full-scale fermenter in order to confidently size and design an agitator for a new fermenter.