(211h) CORE-SHELL AND ENCAPSULATED ADSORBENTS FOR FLOW THROUGH PURIFICATION OF LARGE BIOMOLECULES AND NANOPARTICLES
AIChE Annual Meeting
2022 Annual Meeting
Area Plenary: Adsorption and Ion Exchange - In Honor of Prof. Andreas Seidel-Morgenstern (Invited Talks)
Monday, November 14, 2022 - 5:42pm to 6:00pm
We examine the structural and functional properties of commercial agarose based core-shell resins and develop models to describe the kinetics of binding for proteins with a broad range of molecular mass in single and multiple component systems. We also describe the development and properties of novel adsorbents obtained by encapsulating ceramic hydroxyapatite particles in inert agarose beads for the adsorption of proteins and nucleic acids impurities.