Chemicals & Materials

Bio-Based Materials Step into the Operating Room

September
2012
On The Horizon
Sujata K. Bhatia, M.D., P.E.
A new class of implantable medical materials — constructed from naturally derived and renewably sourced polymers — is poised to transform clinical medicine.

CEP: News Update

September
2012
News Update
Slippery Surface Is Too Slick for Bacterial Films; New Materials Put the Brakes on Infection; ITO Flexes Its Muscles; Control Wrinkles with this Simple Method; and more

Chem Economics: ACC Releases Portfolio of Specialty Chemicals Indexes

September
2012
Chem Economics
T. Kevin Swift
The American Chemistry Council (ACC) has launched a new set of indexes covering nearly 30 segments of the U.S. specialty chemicals market. (The first, which dealt with plastic additives, was discussed in the July issue, p. 13.) This is the first set...

Applied Hydroaeromechanics in Oil and Gas Drilling

October, 2009
An all-in-one reference combining hydrodynamic theory with drilling applications for the design, planning, and optimization of drilling operations Hydromechanical processes underlie the majority of technology operations in drilling and present a crucial concern as the pace and depth of drilling...

Using Automation to Produce Quality Pharmaceuticals

October
2011
Instrumentation
Joseph S. Alford, P.E.
Automation can pay large dividends in the form of reduced process cycle times, lower operational costs, and more-consistent processes for manufacturing high-quality pharmaceutical products.

CEP: News Update

August
2012
News Update
Updates Include: The Natural Gas Debate Continues Smart Material Stays Cool in the Heat Firefly-Semiconductor Hybrid Lights Up Ionic Liquid Improves Hydrogen-Producing Catalyst One-Pot Synthesis Yields Zeolites at Bargain Prices High-Carbon Diet...

Chemical Engineering Faculty Directory: 2009-2010

December, 2009
This faculty directory lists the contact information of all the faculty members, placement administrators, and student organizations of almost 500 worldwide universities and technical institutes offering chemical engineering curricula. This offers a comprehensive reference tool that is unique and...

Selecting Nickel Alloys for Corrosive Applications

May
2007
Materials
Paul Crook
Nickel and its alloys offer resistance to attack by a wide range of chemicals, including acids, alkalis and salts, making these materials suitable for may CPI applications.

Form Nanoparticles via Controlled Crystallization

October
2008
Reactions and Separations
Robert J. Fisher, Thomai Panagiotou
This continuous bottom-up approach allows precise control of the crystallization process to achieve size, distribution and quality goals, as well as realize the benefits of process intensification.

Fermentation Goes Large-Scale

January
2003
Special Section
Aristos Aristidou , J. J. Hahn , Pim van Hoek , Alex Patist
Designing an economically competitive and environmentally sustainable fermentation route means considering the downstream separations needed to capture the final product during the initial process design.

Save Energy Through Automation

January
2010
Instrumentation
Douglas C. White
Identifying the right automation investments — those with low costs and high impacts — can result in millions of dollars in energy savings for petrochemical plants. <br>

Innovations in Food Processing

March
2003
Fluids and Solids Handling
B. G. Swanson, M. F. San Martín, G. V.  Barbosa-Cánovas
Today's savvy consumers want processed foods to look freshly prepared, while still meeting all safety requirements. Conventional thermal treatments are inadequate to fulfill this demand. New nonthermal techniques, such as pulsed-electric fields, are...

An Introduction to Immunity and Vaccines

November
2011
SBE Special Section
Derek Lapiska
An understanding of the basic approach to creating vaccines, as well as how vaccines confer immunity, is essential to developing safe and cost-effective formulations.

Properly Select Equipment for SIP Systems

August
2007
Fluids and Solids Handling
Tony George
Sterilization-in-place (SIP) systems are essential to the operation of many pharmaceutical and biotech facilities. This article reviews design considerations, selection criteria and performance expectations for control valves, regulators, isolation...

Choose Materials for High-Temperature Environments

February
2001
Materials
Peter  Elliott
High temperatures, stresses, and the presence of elements such as oxygen, sulfur, or the halogens can add up to trouble. Here is how to screen candidate alloys for such service.

Rx for Pharma

March
2009
Critical Issues
Girish Malhotra, P.E.
Chemical engineers could hold the key that helps pharmaceutical companies — facing pressure to control rising drug prices and competition from generics — reduce their manufacturing costs.

Chemical Engineering Perspectives on Vaccine Production

November
2011
SBE Special Section
John G. Aunins, Michael E. Laska, Jose M. Otero, Bret R. Phillips
Fundamental chemical and bioprocess engineering principles and tools will be key to developing and manufacturing vaccines and expanding their availability around the world.

Good Drug Therapy: It's Not Just the Molecule - It's the DELIVERY

February
2004
Special Section
Rita D'Aquino
In today's competitive marketplace, biopharmaceutical companies are seeking effective and user-friendly drug-delivery platforms for their drug molecules. Miniaturized, microfabricated and nanofabricated devices that can be implanted in the body are...

Selecting Agitator Seals for Bioprocessing Applications

January
2008
Fluids and Solids Handling
Gregory T. Benz, William Ho Liam Teng
Issues such as sterility, isolation and contamination must be considered when choosing seals for use in biotech and pharmaceutical processes. This overview describes common types of seals and offers guidance on selecting the appropriate seal for...

Keys to Bioreactor Selection

March
2002
Reactions and Separations
John A. Williams
A few basic types of bioreactor designs are used to produce a wide range of products, from antibiotics to foods to fuels. Here's how to pick the best options for your application.

Designing a Facility for API Development

March
2006
Plant Design
Terrence Fay, Yasha Zelmanovich
Kilo labs are instrumental in scaling up the production of active pharmaceutical ingredients. This article discusses the critical factors that must be considered to design such a facility.

Hydrogen: Liability or Asset?

September
2002
Reactions and Separations
Dennis Vauk, Ian Moore, Nick  Hallale
In a petroleum refinery, viewing hydrogen as an asset rather than a liability can lead to increased profits. The key is in the mindset. A typical investor uses money to make money. This article shows you how to use hydrogen to make money.

Selecting Corrosion-Resistant Materials

December
2006
Materials
Francesco Picciotti, Marcello Picciotti
This article looks at some common corrosion-resistant alloys and gasket materials that are available for use in applications with high pressures and temperatures.

Exploring New Paradigms for Bioprocessing

July
2009
SBE Special Section
Jonathan Monk
Disruptive technologies, such as disposable bioreactors, metabolic ?ux models, and glycoengineered yeast, could change the face — and pace — of biomanufacturing.

Clarifying Centrifuge Operation and Selection

August
2004
Fluids and Solids Handling
Victor Norton ,  William Wilkie
Before selecting a centrifuge for your application, understand its principles of operation and investigate the key process variables.

Choose the Right Elastomer

June
2008
Materials
William M. Stahl
Match a material's performance to process conditions to reduce leaks, improve safety and extend the mean time between failures (MTBF).

Streamlining the Validation Process

March
2007
Management
Tim Flanigan, Robert Mackey
Today, validation is no longer an afterthought for the design and construction of a new or renovated process or facility. It is, in fact, recognized as an integral part of the total project. Fully integrated services are now available to ensure a...

Chemical Engineering in the Pharmaceutical Industry: R&D to Manufacturing

October, 2010
This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences...

Hydrogen and Syngas Production and Purification Technologies

December, 2009
Covers the timely topic of fuel cells and hydrogen-based energy from its fundamentals to practical applications Serves as a resource for practicing researchers and as a text in graduate-level programs Tackles crucial aspects in light of the new directions in the energy industry, in particular how...

Handbook of Polymer Solution Thermodynamics

December, 1993
Created for engineers and students working with pure polymers and polymer solutions, this handbook provides up-to-date, easy to use methods to obtain specific volumes and phase equilibrium data. A comprehensive database for the phase equilibria of a wide range of polymer-solvent systems, and PVT...

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