Biological Engineering

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Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

Quality by Design in Pharmaceutical Development

Conference Presentation
AIChE Annual Meeting
Sunday, November 7, 2010 - 7:00pm
More than 70% of the prescriptions in the US are now filled with generic products, and therefore, the industry has the responsibility to continue to...

Systems Biology and Synthetic Biology

March, 2009
The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems...

Piloting Bioreactors for Agitation Scale-Up

February
2008
Reactions and Separations
Gregory T. Benz
This article offers guidance on how to design appropriate experiments to measure scalable data for agitation in both aerobic and anaerobic bioreactors.

Biorefinery Process Economics

October
2005
SBE Special Section
Gregory M. Bohlmann
With oil and natural gas prices surging, bio-based feedstocks are becoming increasingly competitive. This article examines, in depth, the technical and economic aspects of the biorefinery concept.

SBE Special Section: Biopharmaceuticals - Continuous Processing in Upstream Operations

December
2015
SBE Special Section
Chun Chen, Chetan T. Goudar, Huong Le
Perfusion technology offers many benefits over fed-batch processing, such as reducing the size of the bioreactor, which reduces capital costs and enables the use of single-use bioreactor technology. Despite these advantages, a shift to continuous perfusion will likely be gradual.

Understand Discrete Nanoscale Transport

June
2008
On The Horizon
Anh-Tuan Dinh, Samir Mitragotri, Chinmay Pangarkar
Unlike mass, energy and momentum transfer, which are described by continuum equations, the movements and interactions of the nanoscale entitites within a cell constitute the transport phenomenon known as discrete nanoscale transport (DNT).

Fulfilling the Promise of Nanomedicine

February
2006
SBE Special Section
Rita D'Aquino with Tim Harper, Cristina Roman Vas
Leveraging nanotechnology in the life science industries has given scientists new tools with which they have the potential to transform the world of medicine.

Supplemental Nanobiotechnology Tables

February
2006
SBE Special Section
These tables offer a snapshot of the many companies, research organizations and universities working in nanotechnology, nanoscience, nanobiotechnology and other variations of the term that has been coined to describe a revolutionary approach to...

Applications in Drug Delivery and Tissue Engineering

February
2006
SBE Special Section
Ali Khademosseini, Robert Langer
Nanotechnology is an emerging field that could potentially make a major impact on human health. Nanomaterials promise to revolutionize medicine and are increasingly used in drug delivery or tissue engineering applications.

Engineering Organs: Heart and Esophagus

December
2007
SBE Special Section
Buddy D. Ratner
The potential for tissue engineering to transform the practice of medicine is enormous. Chemical engineers will play important roles in this revolution.

Bioseparation Basics

October
2014
Back To Basics
Roger G. Harrison
Bioseparations are critical to the field of biochemical engineering. Each bioseparation process must be tailored to separate, purify, or recover the desired bioproduct. This article gives an introductory overview of filtration and chromatography — two key bioseparation unit operations.

Stem Cell Engineering 101

November
2010
SBE Special Section
Jonathan Monk
Stem cells are poised to transform medical treatments for a host of diseases and malignant conditions. Translating stem cell research into clinical therapies, disease models, and drug-screening platforms will require a combination of sound science...

Technical Entity Trends: Growing Research in Plant Technologies

June
2016
Technical Entity Trends
Gabriel Levesque-Tremblay
Plant synthetic biology is an emerging field that combines engineering principles with plant biology to develop technologies for bioengineering plants. Plant bioengineers are responsible for the emergence of new technologies related to medical...

An Introduction to Mammalian Cell Culture

April
2016
Back To Basics
Tung S. Le, Meghan McCann, Samira M. Azarin, Dr. Wei-Shou Hu
Mammalian cell culture is at the core of biomanufacturing therapeutic proteins and viral vaccines. Find out how mammalian cells are derived and cultivated, and what opportunities this field holds.

2019 AIChE Annual Meeting

November 10-15, 2019
The AIChE Annual Meeting is the premier educational forum for chemical engineers interested in innovation and professional growth. Academic and industry experts will cover wide range of topics relevant to cutting-edge research, new technologies, and emerging growth areas in chemical engineering.

Optimization Methods in Metabolic Networks

March, 2016
This book provides a tutorial on the computational tools that use mathematical optimization concepts and representations for the curation, analysis and redesign of metabolic networks. Such analysis and redesign often requires the calculation of product yield, gene essentiality prediction,...

Hybrid Cell Culture Models for Efficient Process Development

Conference Presentation
AIChE Annual Meeting
Thursday, November 12, 2015 - 3:15pm-5:45pm
Cell culture processes are dynamic systems governed by a large number of influential and highly interacting process variables. Despite the stringent...

Hydrolysis of Ddg

Conference Presentation
AIChE Annual Meeting
Wednesday, November 11, 2015 - 12:30pm-3:00pm
Liquid hot water (LHW) extraction was used as a pretreatment method to separate the hemicellulose fraction from dried distiller’s grain with solubles...

Hydrolysis Kinetics of Woody Biomass: Surface Renewal

Conference Presentation
AIChE Annual Meeting
Wednesday, November 11, 2015 - 8:30am-11:00am
Woody biomass is known to be composed of three major components: cellulose, lignin and hemicellulose. Cellulose is the most stable natural polymer in...

Process Simulation of Biogas to Renewable Liquid Fuels

Conference Presentation
AIChE Annual Meeting
Wednesday, November 11, 2015 - 8:30am-11:00am
Biogas is a product of anaerobic digestion of waste organic sources such as animal manure, food wastes and pretreated lignocellulosic biomass. Biogas...

Investigation of Dissolved Lignin in Autohydrolysis Liquor

Conference Presentation
AIChE Annual Meeting
Tuesday, November 10, 2015 - 3:15pm-5:45pm
Autohydrolysis (water, temperature, pressure) pretreatment of lignocellulosic biomass is a sustainable unit operation that effectively reduces...

Developing a Strategy for Constructing Modular Biosensors

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2015 - 12:30pm-3:00pm
The rapidly increasing toolbox of synthetic biology has allowed numerous advances in the engineering of metabolic pathways. One tool that is largely...

Making Escherichia coli Grow on Methanol

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2015 - 12:30pm-3:00pm
The quest for using methanol as a substrate to produce useful metabolites such as commodity chemicals, chemical precursors, biopolymers,...

From Metabolic Engineering to Metabolomics and Back

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2015 - 12:30pm-3:00pm
Metabolic engineering is a field where the level of a specific metabolite is quite obviously a very important thing, because that metabolite is the...

Tools for Engineering Non-Growth Metabolism

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2015 - 12:30pm-3:00pm
Stationary phase metabolism that is not carbon-limited is ideal for metabolic engineering. Without cell growth, feedstocks can be efficiently...
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