Biological Engineering

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Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

Quality by Design for Generic Drugs: Overview

Conference Presentation
AIChE Annual Meeting
Sunday, November 7, 2010 - 7:00pm
Quality by design is an essential part of the modern approach to pharmaceutical quality. But there is uncertainty in the generic drug industry about...

QbD for Generic Drugs: Modified Release Drug Products

Conference Presentation
AIChE Annual Meeting
Sunday, November 7, 2010 - 7:00pm
The Office of Generic Drugs ensures the therapeutic equivalence and quality of generic drug product pharmaceuticals. This is based principally upon a...

Model-Driven Minimization of the B. Subtilis Genome

Conference Presentation
AIChE Annual Meeting
Sunday, November 7, 2010 - 7:00pm
Bacillus subtilis is a gram positive, sporulating bacteria often utilized in industry as a producer of high quality enzymes and proteins [1]. The...

QbD for Generic Drugs: Oral Suspensions

Conference Presentation
AIChE Annual Meeting
Sunday, November 7, 2010 - 7:00pm
The presentation will be focus on the approach for systematic development of oral suspensions. Suspension is a complex dosage form in which coarse...

QbD in Generic Drug Development: PAT Application

Conference Presentation
AIChE Annual Meeting
Sunday, November 7, 2010 - 7:00pm
A generic drug product is pharmaceutically and therapeutically equivalent to a Reference Listed Drug (RLD) product. It meets the same requirements...

Growth Kinetic Study of Chlorella Vulgaris

Conference Presentation
AIChE Annual Meeting
Wednesday, November 11, 2009 - 7:00pm
Algae are simple autotrophic organisms that produce complex organic compounds from simple inorganic molecules such as carbon dioxide using energy...

Optofluidic SERS Devices for Biomolecular Detection

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2009 - 7:00pm
Recently, Surface-enhanced Raman scattering (SERS) has attracted great attention because of its high sensitivity, label-free detection, and low...

Stability and Reactivity of Enzymatic Papers

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2009 - 7:00pm
Bioactive papers and paper diagnostics are getting a reality for their low cost, selectivity and application flexibility. Critical is the thermal...

Designing Sustainable Options for Bioenergy Crops

Conference Presentation
AIChE Annual Meeting
Monday, November 9, 2009 - 7:00pm
Currently, the complexity and scale dependency of land-use decisions and their impacts are not understood, defined, or described with adequate...

Drug Product Quality by Design: An Industrial Perspective

Conference Presentation
AIChE Annual Meeting
Sunday, November 8, 2009 - 7:00pm
The regulatory quality guidances (Q8 – Q10) have set the expectation to develop pharmaceutical products based on a comprehensive quality by design...

Advanced Biofuels - The Path Forward

Conference Presentation
AIChE Annual Meeting
Sunday, November 8, 2009 - 7:00pm
Oil prices go up and they come down and our ability to forecast them with any real confidence has not been particularly good. A year ago when oil...

Application of QbD Principles to Analytical Methods

Conference Presentation
AIChE Annual Meeting
Sunday, November 8, 2009 - 7:00pm
The same QbD Principles applied to the design of manufacturing processes are applicable to the design of analytical methodology. QbD elements such as...

Update on QbD Implementation: An FDA Perspective

Conference Presentation
AIChE Annual Meeting
Sunday, November 8, 2009 - 7:00pm
Quality by Design (QbD) is a science and risk based approach for pharmaceutical process development and manufacturing that begins with first defining...

Biomass Thermal Conversion

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Wednesday, April 29, 2009 - 10:00am
Papers are on topics related sustatinable supply of a wide variety of biomass feedstocks to meet the needs of evolving liquid fuel demand (...

Advances in Bioprocessing

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Wednesday, April 29, 2009 - 4:30am
Please Note : Advances in Bioprocessing -- Spring Meeting 2009 includes the following recorded presentations: · Biofuel and Biochemical Productions...

Success and Prospects in Bioengineering

Conference Presentation
AIChE Annual Meeting
Sunday, November 16, 2008 - 7:00pm
Chemical engineers have always played an important role in the development of biotechnology. From the first efforts to effectively produce penicillin...

Society for Biological Engineering News

October
2005
SBE Special Section
June Wispelwey
Student Chapters Have Arrived! SBE Frontier Tutorial Second Bioengineering and Nanotech Conference Michael Shuler Wins Inaugural James E. Bailey Award Fishing Out Unusual DNA Enzyme is Linked to Neurological Disease

Biotransformations for a Green Future

October
2005
SBE Special Section
Susan Truesdell
Enzyme and microbial biotransformations offer green chemistry alternatives for performing difficult or non-selective chemical reactions.

Enzyme Discovery: Screening, Cloning, Evolving

October
2005
SBE Special Section
Per Falholt, Glenn Nedwin, Thomas Schaefer
Enzymes are nature’s answer to many industrial and environmental challenges. This article details the latest approaches to enzyme discovery and evolution.

Bioreactor Design for Chemical Engineers

August
2011
Back To Basics
Gregory T. Benz
Fermentation processes are based on chemical engineering principles. Understand these concepts to achieve optimal bioreactor design.

Technical Entity Trends: Welcome to the TENT

January
2016
Technical Entity Trends
Lucy Alexander, Derrick Wu
Welcome to Technical Entity Trends (TENT), a new monthly CEP column written by the staff of AIChE’s Technical Entities (TEs). The TEs are communities of chemical engineers and other professionals that address some of society’s grand challenges:...

Green Chemistry and Engineering: A Pathway to Sustainability

November, 2013
Green Chemistry and Engineering presents the green approach as an essential tool for tacking problems in chemistry. This text covers introductory concepts in general, organic, inorganic, and analytical chemistry as well as biochemistry.

Engineered Protein Templates Synthesize Inorganic Nanomaterials

December
2012
SBE Special Section
Arunagirinathan Adhimoolam, Sarah Heilshorn, Kelly N. L. Huggins, Alia Schoen, David T. Schoen
This powerful biomimetic method is a fast, flexible way to produce a wide range of inorganic nanostructures from a single protein scaffold.

Biology as a Basis for Biochemical Engineering

July
2013
Back To Basics
Sujata Bhatia
Biochemical engineering demonstrates the versatility of the living cell as a miniature reactor. Living cells can be genetically engineered to produce specific proteins, tuned to manufacture novel enzymes, and optimized to guarantee genetic stability and consistent production of desired products.

SBE Special Section: Biopharmaceuticals - Continuous Processing in Downstream Operations

December
2015
SBE Special Section
Todd Przybycien, Professor Nigel Titchener-Hooker
The transition from batch to continuous downstream processing of biologics has been gradual, with some processes integrating continuous and batch operations. A fully continuous, commercial-scale downstream process has yet to be implemented. Find out why, as well as the current status of the technology.

Using Genomic Tools to Improve the Production of Biologics

November
2009
SBE Special Section
Dr. Wei-Shou Hu, Nitya M. Jacob, Wei-Shou Hu, Bernard Liat Wen Loo, and Miranda Yap
Recombinant DNA technology transforms mammalian cells into factories for protein-based therapeutics. New techniques provide chemical engineers with a better understanding of the process as well as the cells themselves.

Algal Biofuels: The Research

March
2011
SBE Special Section
Kuan-Chen Cheng, Kimberly Ogden
The individual technical elements of the algae-to-biofuels process have already been demonstrated at the laboratory scale. Ongoing research seeks to refine the technology to enable scaleup to commercial production.

Recombinant Protein Therapeutics from CHO Cells -- 20 Years and Counting

October
2007
SBE Special Section
Dr. Wei-Shou Hu, Karthik P. Jayapal, Katie F Wlaschin, Wei-Shou Hu and Miranda G. S. Yap
The CHO cell is at its height of technological prominence thanks to its adaptability to various culture conditions and plasticity in the context of genetic alterations. With further research, the application ofCell Culture Strategies based on...

SBE Special Section: Biopharmaceuticals (Full 19-Page Supplement)

December
2015
SBE Special Section
Chun Chen, Chetan T. Goudar, Huong Le, Todd Przybycien, Nigel Titchener-Hooker
SBE Update: Continuous Progress in Biopharmaceuticals; Continuous Processing in Upstream Operations; Continuous Processing in Downstream Operations; A Look at the Regulations

Synthetic Biology: Putting Together the Pieces

July
2015
On The Horizon
Michelle Bryner
Synthetic biology represents a new way of building biological systems via engineering tools and principles. Genetic components and pathways will be created to reprogram organisms, endowing them with novel functions for a wide range of applications.

New Products: December 2015

December
2015
New Products
Instrumentation Temperature Transmitters Feature Dual Sensor Inputs The THZ 3 and TDZ 3 two-wire (loop-powered) temperature transmitters provide an isolated and linear 4–20-mA output proportional to input. They can be configured quickly and easily...

The Blood-Brain Barrier and Drug Delivery

March
2013
SBE Special Section
William Olbricht
To maintain favorable conditions in the brain, the blood-brain barrier limits mass transfer across brain tissue. However, it also restricts the systemic delivery of compounds to treat neurological disorders. Several treatment alternatives to bypass...

SBE Special Section: Lignocellulosic Biofuels - Full 32-Page Supplement

March
2015
SBE Special Section
Tristan R. Brown, Robert Brown, Sergio C. Capareda, Bruce E. Dale, David Edwards, Vonnie Estes, Cesar Granda, Mark Holtzapple, Sagar Lonkar, Darlene Schuster, Charles Wyman
SBE Update; The Need for Biofuels; Producing Biofuels via the Thermochemical Platform; Producing Biofuels via the Sugar Platform; Producing Biofuels via the Carboxylate Platform; Scaling Up Bioenergy Technologies; Commercial-Scale Production of Lignocellulosic Biofuels

SBE Update: The Merging of Bio and Nano

December
2012
SBE Special Section
June Wispelwey
Earlier this year, the Society for Biological Engineering (SBE) organized its Sixth International Conference on Bioengineering and Nanotechnology (ICBN), which focused on bio-nanoscience and bioengineering for translational medicine. The conference...

Bioactive Devices: Uniting Form with Function

March
2013
SBE Special Section
Sujata Bhatia
Bioactive implants that combine a medical device with one or more biologic therapeutic agents show promise for the targeted treatment of complex medical conditions. Implantable medical devices, such as stents, grafts, and joint replacements, are...
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