AIChE | The Global Home of Chemical Engineers

Good Drug Therapy: It's Not Just the Molecule - It's the DELIVERY

February
2004
Special Section
Rita D'Aquino
In today's competitive marketplace, biopharmaceutical companies are seeking effective and user-friendly drug-delivery platforms for their drug molecules. Miniaturized, microfabricated and nanofabricated devices that can be implanted in the body are...

Clarifying Centrifuge Operation and Selection

August
2004
Fluids and Solids Handling
Victor Norton ,  William Wilkie
Before selecting a centrifuge for your application, understand its principles of operation and investigate the key process variables.

Pumping System Head Estimation

February
2005
Fluids and Solids Handling
James Anthony
These spreadsheets highlight losses, uncertainties and value of power used, helping you optimize pumping system designs and save on operating costs.

Tools to Model Multiphase Separation

June
2007
Fluids and Solids Handling
David Connolly, Saeid Mokhatab, Timothy Newton
The flow fields in multiphase separators are often extremely complicated, making it difficult to model such systems. Computational fluid dynamics (CFD) and visual dynamic modeling (VDM) can be used together to overcome some of the challenges.

Use Model-Predictive Control to Improve Distillation Operations

January
2008
Instrumentation
Robert J. Conroy, Umesh Mathur, Robert D. Rounding, Daniel R. Webb
This methodology, based on steady-state and dynamic simulation, can be used to develop the necessary models— and avoid disruptive and costly step testing to the extent feasible.

Predicting Emissivities of Combustion Gases

June
2009
Heat Transfer
Alireza Bahadori, Hari B. Vuthaluru
Use this new correlation, which employs easy-to-solve algebraic equations to estimate gas emissivities, to simplify the design and optimization of boilers, furnaces and other combustion equipment.

Your Personal Genome for $1,000?

November
2009
SBE Special Section
IBM scientists from four fields — nanofabrication, microelectronics, physics and biology — are collaborating to develop a “DNA transistor” that could make obtaining a personalized genome analysis easier, faster, and cheaper — ultimately as low as $...

Measuring and Communicating Sustainability through Eco-Efficiency Analysis

December
2010
Environmental Management
Peter Saling, Bruce W. Uhlman
Eco-efficiency analysis promotes an understanding of the economic and environmental trade-offs over products’ lifecycles, and supports informed, strategic decision-making in all areas of a business, from spurring innovative product development to...

Selecting the Proper Flare System

July
2011
Back To Basics
Adam Bader, Wes Bussman, Charles E. Baukal Jr., P.E.
Flares allow for the safe, effective disposal of gases and liquids, by acting as relief devices when a plant must quickly dispose of product within its system to prevent overpressurization and potential explosions.

Optimize Heat Exchanger Cleaning Schedules

June
2001
Heat Transfer
Bruce A. Barna, Chris D. Gosling, Brendan R. O'Donnel
Get the most out of your heat exchanger by evaluating the trade-offs between a one-time expenditure and reduced operating expenses, increased income, and/or longer operating life span. Brendan R. O'Donnell - Bruce A. Barna - Chris D. Gosling -

Integrate EHS for Better Process Design

February
2002
Process Development
Lisa Bendixen
Get a jump on process development by addressing environmental, health and safety (EHS) issues together early in the design and development cycle. The result will be a better process and lower costs.

Improve Your Reading Efficiency and Speed

March
2003
Career Catalyst
Robert W. Bly
Are you feeling overwhelmed by the daily influx of memos, letters, reports and journals? These tips will help you develop a systematic method for dealing with the endless stream of material that is essential to your job.

Preparing for GHG Inventory Verification

April
2004
Environmental Management
- Lauren M. Sandler, James T. Wintergreen
To ensure that the greenhouse gas inventory is accurate and complete, prepare for eventual third-party verification during the planning and data collection stages.

Properly Select Equipment for SIP Systems

August
2007
Fluids and Solids Handling
Tony George
Sterilization-in-place (SIP) systems are essential to the operation of many pharmaceutical and biotech facilities. This article reviews design considerations, selection criteria and performance expectations for control valves, regulators, isolation...

Analyzing Equilibrium when Noncondensables Are Present

April
2008
Environmental Management
Allen Hatfield
With the simplifying assumption that all of the noncondensable gases exit via the vapor stream, material balances and equilibrium calculations can be used to determine the compositions of the emissions streams leaving a control device.

Examining X-Ray Technology

March
2009
Fluids and Solids Handling
Ray Spurgeon
Use X-ray inspection to see whether your product is contaminant-free and packaged properly.

Successfully Navigate the Negotiation Process

February
2010
Career Catalyst
Lisa L. Walker
Employment negotiations begin even before a job offer is extended. Having a clear plan of action, and an understanding of your objectives and those of your employer, will help you make the most of this important process. <br>

Reduce Your Compressed Air Costs

October
2011
Fluids and Solids Handling
Ron Marshall, Bill Scales
Annual operating expenses for compressed air systems can exceed the equipment’s purchase price. Follow these seven steps to implement efficiency measures that yield cost reductions.

10 Tips for Managing Your Career

July
2001
Career Catalyst
Bettina  Seidman
Get interpersonally fit by improving your work relationships and honing your communication skills

Succeed in Business in Germany and Switzerland

November
2001
Career Catalyst
Leonore  Clauss, Lionel F. Laroche 
Interactions with the Germans and the Swiss may seem easy, but it's important to understand their way of thinking and their approach to doing business.

Use E-mail Effectively

December
2002
Career Catalyst
Gary Blake
These tips will help improve your e-mail style and make sure that your e-mail is effective intrinsically, as well as fitting the new electronic expectations of a wide range of cyber colleagues.

Think Outside the Box to Reduce Wastes

June
2003
Environmental Management
R. Bruce Hartman, Martin C. Welch
Use this audit procedure to evaluate the current performance of your process safety management processes as well as their future viability.

Marketing Your Professional Expertise to Attorneys

December
2003
Career Catalyst
Rosalie  Hamilton
When you see an expert testify in a legal case on TV and think I could do that, you may be right. Here's what you need to know to become a litigation support consultant.

What’s the Price of Steam?

July
2005
Heat Transfer
Robin Smith, Petar Varbanov
Realistic steam prices are necessary for the efficient operation of a chemical production site, both to allocate realistic costs to the different businesses on the site and to provide a true economic incentive for energy conservation.

Building Models from Simulator Runs

January
2006
Computational Methods
Magali de Macedo, Aad van Veldhoven
The design-of-experiments approach has the advantage of providing the framework to build complex models with minimum use of time and effort.

Improving Heat Exchanger Designs

April
2007
Heat Transfer
Christopher A. Bennett, David C. King, R. Stanley Kistler, Thomas G. Lestina
This article defines and explains the factors that affect heat exchanger design margins. With the proper application of design margins, capital costs can be lowered and plant operations improved.

Realizing the Promise of Wireless

May
2009
Instrumentation
Bob Karschnia, Peter Zornio
Innovation drives the growth of wireless technology, as successful applications demonstrate cost savings, reliability, safety, and ease of use.

Making Smarter Clean-Tech Investments

October
2010
Management
William J. Grieco, Adam Javan
Appropriate due diligence can help investors sort through the hype and identify the most viable ventures.

Selecting a Heat Exchanger Shell

June
2011
Back To Basics
Thomas G. Lestina, P.E.
The first step in specifying a shell-and-tube heat exchanger is choosing the right shell to meet process requirements.

Basics of Centrifugal Pump Selection

May
2002
Fluids and Solids Handling
Bernadette Pyzdrowski, Drew B. Schiller, Kimberly Fernandez, Michael B. Smith
Tips for specification and operation that provide for cost-effectiveness and reliability.

Outsourcing Environmental Compliance

October
2002
Environmental Management
Stephen W. Blocki
Save money and reduce risks by contracting responsibility for maintaining compliance to a pollution-abatement expert.

Guidelines for Crystallizer Selection and Operation

October
2004
Reactions and Separations
Wayne Genck
Continuous crystallizers serve a wide range of applications in the chemical process industries. Optimize system performance by heeding these practical design and operating principles, which apply to the forced circulation (FC), draft-tube-baffle (...

Prepare Now for REACH Compliance

March
2005
Environmental Management
Beth Sirull
Pending legislation would require companies that make or use chemicals in the European Union to register those substances.

Designing a Facility for API Development

March
2006
Plant Design
Terrence Fay, Yasha Zelmanovich
Kilo labs are instrumental in scaling up the production of active pharmaceutical ingredients. This article discusses the critical factors that must be considered to design such a facility.

Mother Nature as both Doctor and Patient

November
2006
SBE Special Section
Edwin N. Lightfoot
Once we have grasped some essentials of this riotous, but surprisingly well ordered world, we shall find our transport phenomena background to have real utility.

Use Spreadsheets to Estimate Modeling Parameters

February
2008
Computational Methods
Tomas B. Co
Dynamic process modeling based on non-uniformly sampled data and multiple sampling runs, even for nonlinear systems, can be performed using spreadsheet implementations of the weighted-least-squares (WLSQ) and Runge-Kutta WLSQ methods.

Save Energy Through Automation

January
2010
Instrumentation
Douglas C. White
Identifying the right automation investments — those with low costs and high impacts — can result in millions of dollars in energy savings for petrochemical plants. <br>

Institute News

May
2012
Institute News
Read the latest Institute News reported by CEP.

Keeping Global Teams Going

February
2002
Career Catalyst
Lionel F. Laroche
Global teams can maintain their effectiveness by using the right communication tools, following good communication practices, working at building and maintaining trust, and taking cultural differences into account.

Use Sustainability Metrics to Guide Decision-Making

July
2002
Environmental Management
Beth R. Beloff, Earl  Beaver, Jeanette M. Schwarz
Sustainability provides a framework for integrating environmental, social and economic interests into effective business strategies.

Optimize Power Consumption in Aerobic Fermenters

May
2003
Reactions and Separations
Gregory T. Benz
By performing the necessary pilot work, and rigorously calculating the full-scale performance instead of using simple rules-of-thumb, significant energy savings can be achieved in fermenters.

Conduct Successful Team Meetings

November
2003
Career Catalyst
Barry M. Weinstein
Prepare effective agendas, minutes, status updates, and corrective action reports to make your meetings, as well as your projects, run more smoothly.

Getting Your Message Across

May
2004
Career Catalyst
Margaret Clarke Hunt, Denise Price Hosier
Engineers play an important role in the marketing of products, processes and services. Here's a short course on the basics of marketing communications to help you be effective in that role.

Consider Using Fluoropolymers in Biological Applications

December
2004
Materials
Lauri Jenkins, Sharon Libert, Victor Lusvardi
Even with the use of costly corrosion-resistant alloys, metal contamination continues to occur in the biologics industry, thus reducing product yield and activity. Fluoropolymers are emerging as a viable solution to this problem.

Right-Sizing Environmental Controls

June
2006
Environmental Management
E. Joseph Duckett
Size does matter - and bigger is not necessarily better when it comes to pollution control. It is more important to be the right size than the largest size.

Scaling Fixed-Bed Catalyzed Processes

March
2007
Reactions and Separations
Jonathan H. Worstell
The new parameter introduced here will yield more meaningful results when a fixed-bed reactor is scaled up for process development or scaled down for plant support.

Capturing Carbon from Existing Coal-Fired Power Plants

April
2009
Special Section
Jared P. Ciferno, Timothy E. Fout, Andrew P. Jones, James T. Murphy
DOE's National Energy Technology Laboratory is spearheading R&D on a variety of post-combustion and oxy-combustion technologies to cost-effectively achieve 90% CO2 capture.

Ionic Liquid Pretreatment

March
2010
SBE Special Section
Harvey W. Blanch, Bradley M. Holmes, Blake A. Simmons, Seema Singh
Ionic liquids show promise as lignocellulosic biomass solvents. But is this approach a scientific curiosity or a commercially viable biofuel pretreatment technology?

Engineering a Healthy Body

September
2010
Career Catalyst
Nick Hallale
These basic chemical engineering principles expose common weight loss myths and show you how to get into better shape efficiently and sustainably.

Chemical Engineering Perspectives on Vaccine Production

November
2011
SBE Special Section
John G. Aunins, Michael E. Laska, Jose M. Otero, Bret R. Phillips
Fundamental chemical and bioprocess engineering principles and tools will be key to developing and manufacturing vaccines and expanding their availability around the world.

Controlling Emissions During Cold Furnace Startup

February
2007
Environmental Management
Wes Bussman, Jianhui Hong, Charles E. Baukal Jr., Richard T. Waibel
High carbon monoxide emissions from a furnace while its temperature is being ramped up can exceed permit limits if appropriate measures are not taken. Here are a few suggestions.

Propel Your Pneumatic Conveying System to Higher Efficiency

April
2001
Fluids and Solids Handling
Francisco  Cabrejos, Herman  Purutyan, Thomas G. Troxel
For new and existing installations, there are many system and component choices available. Here’s how to narrow down the options to make the appropriate selection for optimal performance.

Give Memorable Presentations

January
2003
Career Catalyst
Robert W. Bly
These guidelines will help you prepare and deliver a more exciting presentation.

Handling Flammable Liquids

July
2003
Fluids and Solids Handling
James C. Mulligan
Identify electrostatic hazards associated with liquid processing and understand the precautions available to control them.

Control Commissioning Costs

August
2004
Management
D. P. Lal
This procedure for commissioning a large chemical complex can help reduce the time required and minimize expenses.

Pages

Subscribe to AIChE | The Global Home of Chemical Engineers