Bioprocessing

Success and Prospects in Bioengineering

Conference Presentation
AIChE Annual Meeting
November 16, 2008
Chemical engineers have always played an important role in the development of biotechnology. From the first efforts to effectively produce penicillin...

Biolubricants Development, Formulation and Friction Test

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
March 28, 2017
Biolubricants have exhibited a lot of advantages over the conventional lubricants: excellent lubricity, minimizing of corrosion of metal surfaces,...

Cell Therapy Bioprocessing

Archived Webinar
Feb 8, 2011
As cellular therapies are advancing through clinical development and getting closer to market, close collaborations between stem cell biologists, clinical cell processing technologists, and bioengineers will be required for effective commercialization of this new class of drugs. New cell production...

Molecular Bioprocessing as a New Paradigm for Drug Discovery

Archived Webinar
Mar 2, 2010
The drug discovery process is expensive and often inefficient. With the emergence of genomic and proteomic information, the growth of critical molecular targets is rapid. Nevertheless, the development of active, selective, and safe drug candidates (small molecule or biopharmaceutical) has not kept...

Designing Efficient Metabolic Networks for Biofuels Production

Archived Webinar
Jun 25, 2009
Biotechnological processes depend to a large extent on the productivity of the organisms used. Recent advances in systems biology and bioinformatics have made it possible to rigorously analyze the functioning of complex metabolic networks using first principles. Such analysis provides a valuable...

New Products: March 2017

March
2017
New Products
Measurement Equipment Level Transmitters Provide Accurate Measurements in Challenging Applications The Model 2290 unguidedwave radar transmitters and Model 2291 guided-radar transmitters incorporate advanced radar-sensing technology designed for...

New Products: January 2017

January
2017
New Products
Environmental, Health, and Safety Adsorbent Makes Use of Glass Waste The Green Glass Adsorbent Technology is made of recycled LCD-panel glass. This unique material adsorbs heavy metal ions from industrial wastewater, and then desorbs the ions so...

Books: December 2016

December
2016
Books
Hidden Figures: The American Dream and the Untold Story of the Black Women Mathematicians Who Helped Win the Space Race Margot Lee Shetterly, William Morrow, New York, NY, $27.99, 368 pages, Sept. 2016, ISBN: 978-0-062-36359-6 During the labor...

Natural Ecosystem Unit Operations [On Location]

November 13, 2013
Working with a plant site's existing natural resources, chemical engineers can harness ecosystems to mitigate undesirable plant outputs and reduce or eliminate the need for...

Rotating Algal Biofilm Reactor [On Location]

November 11, 2013
A new approach to address the problems of the large land area required for cultivation, culture contamination and the difficult and costly dewatering of the harvested cells in...

Piloting Bioreactors for Agitation Scale-Up

February
2008
Reactions and Separations
Gregory T. Benz
This article offers guidance on how to design appropriate experiments to measure scalable data for agitation in both aerobic and anaerobic bioreactors.

Upgrading of Biomass-Derived Liquid to Clean Fuels

Conference Presentation
AIChE Annual Meeting
November 2, 2012
The objective of this study is to develop and demonstrate a viable economical pathway to produce renewable transportation fuels from cellulosic biomass such as wood chips, forest wastes, and agriculture residues.

Advances in Bioprocessing

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
April 29, 2009
Please Note : Advances in Bioprocessing -- Spring Meeting 2009 includes the following recorded presentations: · Biofuel and Biochemical Productions...

Bioreactor Design for Chemical Engineers

August
2011
Back To Basics
Gregory T. Benz
Fermentation processes are based on chemical engineering principles. Understand these concepts to achieve optimal bioreactor design.

Using Genomic Tools to Improve the Production of Biologics

November
2009
SBE Special Section
Dr. Wei-Shou Hu, Nitya M. Jacob, Wei-Shou Hu, Bernard Liat Wen Loo, and Miranda Yap
Recombinant DNA technology transforms mammalian cells into factories for protein-based therapeutics. New techniques provide chemical engineers with a better understanding of the process as well as the cells themselves.

Algal Biofuels: The Process

March
2011
SBE Special Section
Al Darzins, Eric P. Knoshaug
The production of algal biofuels involves algae cultivation, biomass harvesting and dewatering, lipid extraction, and conversion to fuel.

Principles of Bioprocess Control

November
2009
SBE Special Section
Joseph S. Alford
The use of complex living organisms, process variation, and lack of real-time measurements of key parameters are some of the challenges involved in automating a bioprocess. This article explains an indirect approach to monitoring and controlling a...

Speeding the Design of Bioprocesses

May
2008
SBE Special Section
Sunil Chhatre , Andrew D. Tustian
These experimental and modeling techniques enable the rapid, cost-effective design and scale-up of biopharmaceutical manufacturing in an integrated fashion.

Minimize Scale-Up Risk

March
2010
SBE Special Section
J. Brad Cort, Thomas Pschorn, Bertil Stromberg
Proven commercial-scale equipment already exists for many operations involved in producing biofuels from lignocellulosic feedstocks.

Mother Nature as both Doctor and Patient

November
2006
SBE Special Section
Edwin N. Lightfoot
Once we have grasped some essentials of this riotous, but surprisingly well ordered world, we shall find our transport phenomena background to have real utility.

Keys to Bioreactor Selection

March
2002
Reactions and Separations
John A. Williams
A few basic types of bioreactor designs are used to produce a wide range of products, from antibiotics to foods to fuels. Here's how to pick the best options for your application.

Scaling Up Research to Commercial Manufacturing

November
2010
SBE Special Section
Erika Lapinskas
The production of stem-cell-based therapeutic products in large quantities is more complex than manufacturing molecular drugs. Scale-up and scale-out challenges arise related to the type of stem cell, cell expansion and banking, sterile handling,...

Bioprocess Design for a Novel Vaccine

November
2006
SBE Special Section
Barry C. Buckland
The challenges of vaccine development are not limited to identification of suitable antigens, adjuvants and delivery methods, but include regulatory, technical and manufacturing hurdles in translating a vaccine candidate to the clinic.

Fermentation Goes Large-Scale

January
2003
Special Section
Aristos Aristidou , J. J. Hahn , Pim van Hoek , Alex Patist
Designing an economically competitive and environmentally sustainable fermentation route means considering the downstream separations needed to capture the final product during the initial process design.

Integrating Single-Use Filtration Systems

January
2003
Special Section
Holly Haughney
Disposable filtration systems are gaiing popularity in the pharmaceutical arena. This article defines the equipment, specifications, applications and potential advantages of single-use filters and ancillary equipment.

Consider Using Fluoropolymers in Biological Applications

December
2004
Materials
Lauri Jenkins, Sharon Libert, Victor Lusvardi
Even with the use of costly corrosion-resistant alloys, metal contamination continues to occur in the biologics industry, thus reducing product yield and activity. Fluoropolymers are emerging as a viable solution to this problem.

Avoid the Pitfalls of Bioprocess Development

August
2006
Process Development
Mukesh Doble
This article presents the challenges that an engineer might encounter when designing or scaling up bioprocesses and offers practical solutions, including those cited in literature.

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