The Synthesis and Characterization of Bimetallic Nanoparticles Made By Bacteria for Biomedical Applications
- Conference: Mammalian Synthetic Biology Workshop
- Year: 2018
- Proceeding: Fifth International Mammalian Synthetic Biology Workshop
- Group: Poster Session
- Time: Saturday, May 5, 2018 - 5:30pm-6:30pm
In this research, we present the environmentally-friendly and cost-effective synthesis of CdSe and ZnSe bimetallic nanoparticles using living bacteria, in an entirely green-synthetic approach. Bacteria are cultured in media that is inoculated with both sodium selenite (Na2SeO3) and cadmium chloride (CdCl2)/zinc chloride (ZnCl2) as metallic precursors for the nanoparticles. Using a detoxification process, bacteria can reduce metallic salt ions dissolved in elemental metallic nanoparticles with unique electronic properties.
Nanoparticles generated by bacteria, as other biogenic products, can be purified by disruption of the cell membranes and they can be used as antibacterial agents against both Gram-negative and Gram-positive bacteria, showing low cytotoxicity for human cells. Therefore, these metallic nanoparticles can be used for biomedical and imaging applications, indicating that green synthetic approaches can overcome the main limitations of traditional quantum dots synthesis methods.