(206a) Measurement and Control of High Shear Granulation by Image Processing
AIChE Spring Meeting and Global Congress on Process Safety
2006
2006 Spring Meeting & 2nd Global Congress on Process Safety
Fifth World Congress on Particle Technology
Process Analysis Techniques in the Pharmaceutical Industry
Wednesday, April 26, 2006 - 1:00pm to 1:20pm
High shear granulation has many advantageous points that it produces spherical and well-compacted granules in relatively short time and the equipment itself is very simple. However, granulation in a high shear mixer is very sensitive to even minor changes in moisture content, amount of binder, physical properties of starting materials and the operating conditions. Therefore, there is a great need for reliable system for process monitoring and control of granule growth. In this study, on-line measurement and control of high shear granulation is conducted by means of a novel image processing system, which basically consists of an image processing device and a feedback control system. Scale-up of high shear granulation is also conducted by the image processing system and validity of the system is discussed.
Checkout
This paper has an Extended Abstract file available; you must purchase the conference proceedings to access it.
Do you already own this?
Log In for instructions on accessing this content.
Pricing
Individuals
AIChE Pro Members | $150.00 |
AIChE Graduate Student Members | Free |
AIChE Undergraduate Student Members | Free |
AIChE Explorer Members | $225.00 |
Non-Members | $225.00 |