Quantitative Approaches to Disease Mechanisms and Therapies

Co-chair(s):
Rumschitzki, D., Department of Chemical Engineering, City College of City University of New York

This session highlights applying conventional (e.g., reaction and transport phenomena) and emerging (e.g., dynamical systems and statistical mechanics) concepts from (bio)chemical engineering to aid in understanding disease mechanisms and designing therapies. Submissions that integrate experimental work with simulation and that demonstrate a clear connection between engineering fundamentals and disease pathophysiology are particularly encouraged.

Papers:
12:30 PM
(158a) Quantitative Imaging of Human Rhinovirus Gene Expression Kinetics at the Single-Cell Level
12:48 PM
(158b) CAM/Camkii Mediated Remodeling of PDZ Domains and the Inhibitory Influence of Syngap in the Post-Synaptic Density
1:06 PM
(158c) A Mathematical Investigation of Chemotherapy-Induced Peripheral Neuropathy
1:24 PM
(158d) A Kinetic Model of Tumor-Induced Bone Disease Predicts Complex Response Dynamics to Bone-Specific Mechanical Forces and Drug Perturbations
1:42 PM
(158e) Characterizing the Role of Biomembrane Phase Separation in the Function and Regulation of the Drug Target Gamma-Secretase
2:00 PM
(158f) Model-Based Diagnosis, Management, and Treatment of Chronic Obstructive Pulmonary Disease (COPD)
2:18 PM
(158g) Integrative Analysis of Free Fatty Acid-Induced NF?B Activation in Macrophages: A Step Towards the Quantitative Understanding of Inflammation Induced By Obesity
2:36 PM
(158h) It Takes Two to Tango! Examples of Experiments/Simulations Combinations to Tackle Cancer Biology
Topics: 
Medicine
Systems Biology

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Individuals

AIChE Members $150.00
AIChE Graduate Student Members Free
AIChE Undergraduate Student Members Free
Non-Members $225.00