The Toxic Substances Control Act (TSCA) requires the U.S. Environmental Protection Agency (USEPA) to establish a risk process evaluation to determine whether a chemical poses a considerable risk to the human health or the environment. Consequently, as a part of the procedure for chemical risk evaluation, the USEPA has developed models to understand the relationship between a chemical and a potential receptor, either human or the environment. As part of the effort to meet the TSCA requirements, USEPA published in 2016 an initial list of the first 10 chemicals substances to address risk evaluation. In the conceptual models developed for the 10 substances, the pathways considered can be expanded to releases of chemicals when these are transferred to an off-site facility for their recycling, recovery, and/or reuse, as well as waste treatments regulated by any USEPA statute different to TSCA. Therefore, for dealing with the current needs and considering that the current TSCA Chemical Substance Inventory lists around 85,000 chemicals, this work proposes an end-of-life data-reconciliation and learning-from-data framework. This approach is based on existing USEPA databases for predicting releases that occur following the abovementioned end-of-life management at off-site facilities. The data-reconciliation framework will be useful to support TSCA risk evaluation by means of rapid estimation of industrial chemical releases during end-of-life management scenarios, which are not currently analyzed. Therefore, a chemical substance under interest might be tracked in its composed industrial life-cycle and a learning-from-data generalization would be applied for existing and new chemical substances in the U.S. market which are not currently reported in USEPA databases.
The views expressed in this abstract are those of the authors and do not necessarily represent the views or policies of the U.S. Environmental Protection Agency.