(577f) Process Control Strategy for Synthetic Continuous Manufacturing
AIChE Annual Meeting
Wednesday, November 13, 2019 - 5:15pm to 5:36pm
A âVirtual Plant for Synthetic Continuous Manufacturingâ was developed on the grounds of a systems-based modelling platform. Model components were integrated to form the end-to-end process model, with which in silico studies (sensitivity analysis, uncertainty propagation, etc.) are performed to identify the key process parameters that will affect the critical quality attributes. Here we present the development and testing of an integrated advanced process control strategy enabled by the systems-based model. This approach is envisioned to support regulatory filings for CM processes. Development of a virtual plant for synthetic CM enables us to predict process performance and product quality in a real plant environment.