(174p) Nanostructure Control of Biosensing Materials: From Fundamental Research to Industrial Instrument

Zhenyu Chu, Wanqin Jin

State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, 5 Xinmofan Road, Nanjing 210009, P.R. China)

Email: zychu@njtech.edu.cn

Although numerous biosensors have been developed in the last decade, rare achievements can be successfully transferred to products for real applications. High-cost, low sensitivity and unsatisfactory accuracy are essential problems to block the large-scale production of biosensor instruments. Nanomaterials have been confirmed to possess obvious advantages in the biosensing application. However, limited to the preparation methods, most of nanomaterials can hardly form their stable and regular nanostructures in large-scale. In this presentation, a brief introduction of my group work will be given to address above issues. Focused on the different crystallization behaviors of various materials, a series of novel synthesis approaches have been developed, such as electrostatic self-assembly, aerosol deposition, monolayer molecule modified deposition, and etc. Using these methods, various biosening materials with lots of regular nanostructure have been harvested in large-scale. These special nanomaterials were further treated as the printing inks for the production of miniaturized biosensing chips. The industrial biosensor instrument has been produced and already applied in many fermentation factories and research institutes for the in-situ and ex-situ components detection.

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