(741e) Proteins at Extreme Conditions: From Understanding Life to Parctical Applications
AIChE Annual Meeting
Friday, November 2, 2018 - 9:40am to 10:05am
We use molecular simulations combined with advanced sampling methods and dimensionality reduction techniques to shed light onto how extreme conditions affect proteins which are one of the major building blocks of life. Specifics areas of interest include ionic-liquid induced effects on protein folding mechanisms and kinetics, protein stability in aqueous inorganic solvents with direct applications in novel drug encapsulation methods, and the phase behavior of proteins as a response to protein-water interactions in the temperature-pressure space.