(198s) Nanoclustering of Salicylic Acid in Organic Solvents
AIChE Annual Meeting
2018 AIChE Annual Meeting
Nanoscale Science and Engineering Forum
Poster Session: Nanoscale Science and Engineering
Monday, October 29, 2018 - 3:30pm to 5:00pm
My research focuses on the study of nanoclusters formed in salicylic acid as a function of time in different organic solvents. Salicylic acid, an anti-fungal and anti-inflammatory drug, is used in cosmetic industry. With the use of dynamic light scattering, nanoclusters of salicylic acid were studied in ethyl acetate, acetonitrile, methanol and acetic acid solutions at different concentrations at an isothermal condition for a period of 72h. The solutions are undersaturated, saturated and supersaturated at 25°C. With the change in concentration in different solvents, a trend in order of clustering for different solvents was observed, which holds good for the prediction of nucleation order obtained earlier. At all times, the increase in size is observed which states the order of clustering in different solvents. However, these trends tend to change over the period of time. The one with lower cluster size in undersaturated solutions obtains higher cluster size when the solutions are supersaturared however vice versa is also found to be true. In all solvents, a similar size is obtained at saturated concentration.
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