(178b) Molecular Technologies for Robust Detection of Proteins in Bodily Fluids

Authors: 
Sikes, H. D., Massachusetts Institute of Technology
Infectious diseases worldwide are either undiagnosed or incorrectly diagnosed at a staggering rate because diagnostic techniques that are feasible in the US are not feasible worldwide. An analysis of this problem will be presented along with two molecular technologies that my lab has developed for the detection of proteins in bodily fluids. Engineered binding proteins for sample capture and detection and photo-redox catalyzed polymerization reactions for colorimetric signal amplification will be demonstrated to simultaneously meet performance metrics while also meeting practical constraints set forth by the World Health Organization.