(165a) Functionalization of Graphene By Using Protein Engineering
- Conference: AIChE Annual Meeting
- Year: 2017
- Proceeding: 2017 AIChE Annual Meeting
- Group: Topical Conference: Nanomaterials for Applications in Energy and Biology
Monday, October 30, 2017 - 12:30pm-12:55pm
We have designed peptide specific in binding to the graphene surface non-covalently. We believe this would be helpful in designing sensors that could be advantageous in detecting specific molecules of interest. In this study, we employed surface characterization of graphene surface using time of flight secondary ion mass spectroscopy, atomic Force Microscopy and theoretical biophysics studies to investigate the peptide-graphene interface interactions. We found peptide forms self-assembly on graphene surface, and have high specificity towards graphene surface forming hydrophobic and Ï-Ï interactions. Further, we introduced another protein on the functionalized peptide-graphene surface to check the sensing ability of the device, our results shows the device could be advantageous in designing accurate and specific biosensors for comprehensive analysis of protein molecules.