(72e) A Novel Pathway to 1,5-Pentanediol without the Use of Noble Metals
We have developed a new route to synthesize 1,5-pentanediol in high yields from the hemicellulose fraction of lignocellulosic biomass. Previous work focused on direct hydrogenolysis of the fully hydrogenated form of furfural, tetrahydrofurfuryl alcohol, to 1,5-pentanediol with RhRe catalysts [3,4]. Our new multi-step process uses a combination of heterogeneous acids and supported base metal catalysts.Â The ability to use base metal catalysts stems from the improved reactivity of a key reaction intermediate.
In this presentation, we will focus on mechanistic studies used to determine why the new reaction intermediate is more active than tetrahydrofurfuryl alcohol and why base metals can be utilized for this reaction system. Experiments were performed with nuclear magnetic resonance (NMR) spectroscopy and in situ attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) to help identify reaction intermediates.
 Lux Research, Bio-based Materials and Chemicals Intelligence Service
 MarketandMarkets Report on 1,6-Hexanediol
 Chia, M. et al. Journal of the American Chemical Society. 2011, 32, 12675-89.
 Koso, S. et al. Chemical Communications. 2009, 15, 2035-2037.