(383g) Identification of Magnetic Nanoparticles to Eradicate Cancer Cells Using the Hyperthermia Approach – a Computational Search Approach
Hyperthermia treatment of cancer cells has been one of the most promising ideas of last decade. The theory is to design materials which are very efficient in targeting the cancer cells. The designed particles are to have magnetic properties such that at certain magnetic field conditions the particle develops a higher temperature than the surrounding atmosphere/environment.
This project aims to investigate a way to model magnetic nanoparticle behavior in the presence of different magnitudes of magnetic fields. The aim is to model Brownian and Neel relaxation parameters to determine the heat generated by different MNPs to study which is best suited for hyperthermia treatment of cancer cells. For that, approaches were used to determine AC susceptibility of the out-of-phase particles which was then used in a 3-D model containing healthy and cancer cell. The 3-D model is used to determine temperature output for such materials in the presence of an optimal magnetic field.
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