Mechanistic Understanding and Characterization of the Film Coating Process | AIChE

Mechanistic Understanding and Characterization of the Film Coating Process


Pandey, P., Bristol-Myers Squibb


Chaudhuri, B., University of Connecticut

The film coating is a common unit operation in food, pharmaceutical, chemical, nutraceutical and metallurgical industries. It provides functional coating with additional roles despite several challenges that impact the product quality and cause problems, such as chipping, blistering, picking, and film cracking. The role of modeling has become more prominent in process understanding as the models can be used for virtual experiments to reduce number of actual experiment and map out the design space. This session is devoted to the implementation of novel mechanistic studies and models that assist the design, characterization, optimization and scale up of film coating process. Modeling research including DEM, Monte Carlo, CFD, Population balance, thermodynamic or other approaches would link critical operating conditions to the coating quality and uniformity.



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