Applications of Continuous Processing in the Manufacture of Pharmaceuticals: Drug Substance II

Chair(s):
Nayak, S., AbbVie
Co-chair(s):
Albrecht, J., Bristol-Myers Squibb

Enabled by new technology, continuous processing offers new methods of increasing safety, selectivity, and yield for chemical and biochemical processes. Improved control over process streams enables operation at extreme conditions with reduced sensitivity to scale-up effects. This session will focus on applications of continuous processing to the production of drug substances or their intermediates.

Papers:
3:15 PM
(361a) Optimal Startup of a Continuous Pharmaceutical Process
3:40 PM
(361b) Operation Strategy Development for Grignard Reaction in a Continuous Stirred Tank Reactor
4:05 PM
(361c) A Computational Analysis of a Combined Cooling Anti-Solvent Continuous Crystallization Cascade: A Paracetamol/Methanol/Water Case Study
4:30 PM
(361d) Obtaining Pure Enantiomers and Co-Crystals Using Continuous Preferential Crystallization: A Process Development Investigation Using Population Balance Models
4:55 PM
(361e) Process Modeling, Simulation and Optimization for Continuous Pharmaceutical Manufacturing (CPM) of Ibuprofen
5:20 PM
(361f) Continuous Purification of Active Pharmaceutical Ingredients Using Multistage Organic Solvent Nanofiltration Membrane Cascade

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2014 AIChE Annual Meeting
AIChE Members $150.00
AIChE Graduate Student Members Free
AIChE Undergraduate Student Members Free
Non-Members $225.00
Pharmaceutical Discovery, Development and Manufacturing Forum only
AIChE Members $100.00
AIChE Food, Pharmaceutical & Bioengineering Division Members Free
AIChE Graduate Student Members Free
AIChE Undergraduate Student Members Free
Non-Members $150.00