(577d) Functional Hybrid Nanomaterials for Biosensors

Authors: 
Lee, J., Pohang University of Science and Technology


Self-assembled nanostructured materials attracted much attention due to well-defined porous structures. Various types of mesostructured materials have been synthesized via self-assembly method employing surfactants and block copolymers. Here, we present synthesis of self-assembled nanostructured materials such as mesoporous carbons and silicates and their applications to biosensors. Large cellular porous silica materials were synthesized by the self-assembly of commercially available block copolymers, P123. One-pot multi-catalyst system, so called “nanofactory”, was developed entrapping magnetic nanoparticles and oxidases in large cellular mesoporous silica with high loadings of simultaneously above 40 wt% MNPs and 20 wt% enzymes. Our approach provided highly loaded MNP system and any highly loaded enzymes with superior activity, stability, and reusability, thereby making further applications as versatile sensors for detecting DNA, protein, and cell highly promising. A conductive nanocomposite consisting of Fe3O4 magnetic nanoparticles (MNPs) and oxidative enzyme co-entrapped in the pores of mesoporous carbon is fabricated for highly efficient and robust electrochemical biosensing platform.