(127f) Increasing DNA Correlation Length by Nanoscale Confinement | AIChE

(127f) Increasing DNA Correlation Length by Nanoscale Confinement

Authors 

Lin, P. - Presenter, Academia Sinica
Chou, C. - Presenter, Academia Sinica


We investigate the effect of sub-persistence length confinement on the correlation length of DNA molecules. In strong
slit confinement, the segmental correlation length of DNA molecules have two components -- in the confined
and unconfined dimensions. In the confined dimension, the segmental correlation length is controlled by the slit height. In the
unconfined dimension, the segmental correlation length increases as the slit height decreases. We characterize this effect,
and generalize how this affects the entropic elasticity of confined DNA molecules. In addition, we discuss the structure of
dense strongly confined semi-flexible polymers and effects on thermodynamic properties.