(11h) Ultra-Sensitive Glucose Detection Using Copper Nanowires

Su, L., University of Connecticut
Jia, W., University of Connecticut
Lei, Y., University of Connecticut
Zhang, Y., Chongqing University
Hou, C., Chongqing University
Huo, D., Chongqing University

The detection of glucose, which is important in the diagnosis of diabetes and quality control of fermentation and food, accounts for about 85% of the entire biosensor market. In this work, both enzymatic and non-enzymatic glucose biosensors were constructed on the basis of copper nanowires synthesized by wet chemistry. The as-prepared copper nanowires were then characterized by scanning electron microscopy, transmission electron microscopy, and X-ray diffraction. In the mode of enzymatic glucose sensing, the reduction of hydrogen peroxide was first investigated. The limit of detection for hydrogen peroxide was 200 nM at -0.2 V (vs. Ag/AgCl 3 M KCl) which provides a prospective route for the detection of glucose with the incorporation of glucose oxidase. In the mode of non-enzymatic glucose sensing, an impressive detection limit as low as 50 nM with a sensitivity of 5970 μA·cm-2·mM-1 was obtained.