(548d) Self-Assembled Nanostructured Materials for Biosensing, Biocatalysis and Biofuel Cells

Self-assembled nanostructured materials attracted much attention due to well-defined porous structures. Various types of mesostructured materials have been synthesized via self-assembly method employing surfactants and block copolymers. Here, we present synthesis of self-assembled nanostructured materials such as mesoporous carbons and mesoporous metal oxides and their applications to biosensors and biofuel cells. For the preparation of mesoporous carbons and metal oxides with large pores through ?one-pot' synthesis, block copolymers such as PI-b-PEO and PS-b-PEO were synthesized through anionic polymerization and atom-transfer radical polymerization (ATRP) method. Large cellular porous silica materials were synthesized by the self-assembly of commercially available block copolymers, P123. One-pot multi-catalyst system, so called ?nanofactory?, was developed entrapping magnetic nanoparticles and oxidases in large cellular mesoporous silica with high loadings of simultaneously above 40 wt% MNPs and 20 wt% enzymes. Our approach provided highly loaded MNP system and any highly loaded enzymes with superior activity, stability, and reusability, thereby making further applications as versatile sensors for detecting DNA, protein, and cell highly promising.