(287l) Single-Walled Carbon Nanotubes as near-Infrared Fluorescence and Raman Labels Conference: AIChE Annual MeetingYear: 2005Proceeding: 2005 AIChE Annual MeetingGroup: Particle Technology ForumSession: Particle Technology Forum Poster Session Time: Tuesday, November 1, 2005 - 6:00pm-8:30pm Authors: Heller, D. A., Massachusetts Institute of Technology Strano, M. S., Massachusetts Institute of Technology Eurell, T. E., University of Illinois at Urbana-Champaign Baik, S., Sungkyunkwan University Nucleic acid-encapsulated single-walled carbon nanotubes show Raman scattering and near-infrared fluorescence emission within live mammalian cells in long-term culture. Raman scattering of nanotubes was observed within live murine 3T3 and myoblast stem cells, remaining visible for 3 months and also after the H&E staining procedure. Nanotube fluorescence is in the near-infrared region and does not photobleach under prolonged excitation, permitting continuous monitoring of the cells for experiments lasting hours. Fluorescence emission remained visible after a week in culture and exhibited spectral changes within the cells, leading to possible optical sensors. Nanotubes were taken into endosomes and remained after multiple cell divisions, allowing long-term sensing and labeling experiments.