Engineering (in) Human Cells Using Genome Editing

Originally delivered Feb 24, 2021
  • Type:
    Archived Webinar
  • Level:
  • Duration:
    1.25 hours
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The field of genome editing is experiencing a renaissance driven primarily by the repurposing of an immune response system utilized by bacteria and archaea. This system is characterized by the presence of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) stored in host genomes as memories of phage-bacteria interactions. The use of the CRISPR system in higher organisms (including mammalian cells and animal models) has spurred myriads of applications critically relevant to agriculture, biomanufacturing, and human health. We discuss results at the interface of synthetic biology and genome editing with particular emphasis on engineering biological networks with applications in gene therapy.


Leo Bleris

Leonidas Bleris is an Associate Professor and Cecil H. and Ida Green Professor in Systems Biology Science, with the Bioengineering Department of the University of Texas at Dallas. Before joining UTD, Bleris was a Postdoctoral Fellow at the FAS Center for Systems Biology at Harvard University. Bleris earned a Ph.D. in Electrical Engineering from Lehigh University in 2006. He received a Diploma in Electrical and Computer Engineering in 2000 from Aristotle University of Thessaloniki, Greece. Bleris was awarded the Christine Mirzayan Science and Technology Policy Graduate Fellowship from...Read more

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