This course will emphasize the importance of designing therapeutic proteins and vaccines for manufacturability. Neil Dalvie will give examples of improving manufacturability of multiple vaccines for rotavirus and COVID-19. The lecture will demonstrate how simple, rational, protein engineering to improve manufacturing can accelerate clinical translation of therapeutics, and should be applied early in drug discovery and design. The utility of alternative microbial hosts for production of therapeutic proteins will be discussed. Fast-growing microbes enable large-scale, low-cost processes, and facilitate rapid product testing and iteration
Webinar content is available with the kind permission of the author(s) solely for the purpose of furthering AIChE’s mission to educate, inform and improve the practice of professional chemical engineering. All other uses are forbidden without the express consent of the author(s). For permission to re-use, please contact chemepermissions@aiche.org.
AIChE Practice+ provides learners with opportunities to work on real-world challenges through industry internships and competitions.
With AIChE Career Discovery®, we'll help you to identify aptitudes and skills you’ll need in order to achieve your full potential at various career stages.
AIChE Credential validates your proficiency with potential employers in areas such as process intensification, safety, sustainability and others.