Complimentary Webinars

Through June 30, AIChE members will receive complimentary, unlimited access to live and on-demand AIChE webinars by purchasing them with their newly increased number of credits. See more resources.

QbD in Development of Film Coated Tablets: A Risk Assessment Based Doe Towards a Robust Product and Process

Source: AIChE
  • Type:
    Conference Presentation
  • Conference Type:
    AIChE Annual Meeting
  • Presentation Date:
    November 19, 2014
  • Duration:
    30 minutes
  • Skill Level:
  • PDHs:

Share This Post:

The principles of Quality by Design (QbD) were applied during the formulation development of a film-coated tablet. A risk based approach was used to identify the impact of formulation components and process parameters on the critical quality attributes of the coated tablets. Formulation composition and manufacturing process parameters were defined by carefully constructed design of experiments with focus on impact to critical quality attributes of the final dosage form at release and on shelf-life. The case study will also highlight the integration of process analytical tools (PAT) to monitor in-process material attributes together with parametric controls to ensure a robust and cost effective strategy to transfer and scale-up at the commercial manufacturing site.
Once the content has been viewed and you have attested to it, you will be able to download and print a certificate for PDH credits. If you have already viewed this content, please click here to login.



Do you already own this?



AIChE Member Credits 0.5
AIChE Members $15.00
AIChE Graduate Student Members $15.00
AIChE Undergraduate Student Members Free
Non-Members $25.00