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Batch vs. Continuous

Tieri, S., DuPont

Early-stage process development to introduce new molecules is often performed in a batch mode. This process steps typically include synthesis, separation, and purification. However, when the development team explores the commercial viability of the new process technology, the decision of batch vs. continuous operating mode is critical. Depending on the process technologies and materials, many factors and potential tradeoffs need to be considered when identifying the most optimal operation mode. Examples include process safety, complexity, product form & quality, production volume, manufacturing cost, investment & physical footprint, production time, location, waste generation, sustainability, and commercialization timeline. This session will cover how the differences in the benefits & risks for these aspects impact the batch vs. continuous process decision and resulting commercial viability.



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