(327k) DNA Origami for Nanoparticle Organization and Plasmonic Applications
AIChE Annual Meeting
Tuesday, November 15, 2022 - 2:40pm to 2:53pm
We developed DNA origami hinges that can bind AuNPs with different strength on either arm. Different single stranded (ss) DNA overhangs are available for binding on each arm of the hinge that are complimentary to ssDNA conjugated AuNPs. Longer strands form a stronger bond which will have a different melting temperature allowing the hinge to open and close without releasing the AuNP completely. FRET reporters were used to study the kinetics of hinge actuation with bulk heating and laser excitation. These results have led to the development of higher order hinge structures that allow for the organization of multiple AuNPs into waveguide structures.