(169g) COVID-19: Prevent Infection, Diagnosis and Vaccination Using Nanotechnology | AIChE

(169g) COVID-19: Prevent Infection, Diagnosis and Vaccination Using Nanotechnology

Authors 

Mahmoud, M. S. - Presenter, Al-Azhar University Faculty of Medicine
Dabbish, A. M. - Presenter, the American University in Cairo
Mahmoud, A. S., Housing and Building National Research Center
The world has been struggling with the major health crisis of the coronavirus disease (COVID-19) pandemic since December 2019. The highly virulent nature and the mutation rates of the novel virus resulted in less sensitive detection techniques. The main objective of this review paper is to present the possibility of using nanotechnology for COVID-19 prevention, diagnosis, and for developing vaccination. There are different research activities conducted using dissimilar types of masks to control COVID-19, and their results showed that using single fabric mask with holes was not effective for filtering coronavirus 2019, however, the charged PVDF nanofiber prevent fast-spreading of coronavirus especially COVID-19 and the filtration efficiency may reach 98%. Many researchers suggested that nanosorbents can be used to adsorb COVID-19 virus depending on size, surface area, and the presence of appropriate functional groups. The color of nanosorbents changes relatively by increasing the amount of sorbent virus from the air (virus concentration) and can be measured using different spectra techniques. Nanotechnology can also be an ideal solution to overcome the drawbacks of inactivated vaccines. The common traditional vaccines which depend on live-attenuated or inactivated pathogens present different risks from reflection to pathogenic virulence or guide to a weak immune response. So, the non-traditional vaccines based on nanoparticles can enhance strong immunogenicity and antigen presentation by controlling the surface, shape, size and functional groups.

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