PAT and Process Monitoring in Crystallization Development and Manufacturing
- Conference: AIChE Annual Meeting
- Year: 2020
- Proceeding: 2020 Virtual AIChE Annual Meeting
- Room: Separations Division (02)
- Location: PreRecorded+
- Time: Thursday, November 19, 2020 - 8:00am-9:00am
Crystallization is an industrially important unit operation for purification and formulation of a wide range of chemical products, including pharmaceuticals and fine chemicals. Developing a crystallization process can be challenging, often complicated by multiple components and requirements that the solids are consistently isolated in the desired polymorphic forms, compounds, or solvates. Control of particle size distribution may be needed to avoid difficult filtrations or high impurity content. This session is focused on providing examples where Process Analytical Technologies (PAT) or other means of process monitoring have been used in the development or manufacturing of crystallization processes. PAT applications may include various spectroscopy (FTIR, NIR, Raman), particle size and counting techniques (FBRM, PVM), and other on-line or in-line monitoring or sensing techniques. Novel approaches and methodologies to drive crystallization development or control manufacturing crystallization processes are of particular interest.
Paper abstracts are public but to access Extended Abstracts, you must first purchase the conference proceedings.
Do you already own this?
Log In for instructions on accessing this content.
|AIChE Emeritus Members||$105.00|
|AIChE Graduate Student Members||Free|
|AIChE Undergraduate Student Members||Free|