Conference Program
TimeTitle Sunday, June 153:45-7:00 PMRegistration4:45-5:30 PMOpening Reception and Poster Session (Poster Group 1)5:30-6:15 PMPlenary Lecture: A 15-Year Journey to Figure out How to Derive the Most Economic Value from Metabolic Engineering- Christophe Schilling,...
Time |
Title |
Sunday, June 15 |
|
| 3:45-7:00 PM | Registration |
| 4:45-5:30 PM | Opening Reception and Poster Session (Poster Group 1) |
| 5:30-6:15 PM | Plenary Lecture: A 15-Year Journey to Figure out How to Derive the Most Economic Value from Metabolic Engineering- Christophe Schilling, Genomatica |
| 6:15-7:00 PM | Plenary Lecture: Perspectives on Creating & Scaling-up Better Energy Solutions- Vineet Rajgarhia, Total |
| 7:00-7:30 | Opening Reception continued |
Monday, June 16 |
|
| 7:00 AM-12:00 PM | Registration |
| 7:30-8:00 AM | Breakfast |
| 8:00-10:05 AM | Session 1: Parts to Protein Scale Engineering |
| Session Chairs: Timothy Lu, MIT and Fernando Valle, Codexis | |
| 8:00-8:25 AM | Invited Speaker: New Enzymes by Evolution: Expanding Nature’s Catalytic Repertoire- Frances Arnold, Caltech |
| 8:25-8:50 AM | Synthetic Enzymes for Synthetic Biology- Alexandre Zanghellini, Arzeda |
| 8:50-9:15 AM | Invited Speaker: In Vivo Evolution of Enzymes and Metabolic Pathways for the Production of Chemicals- Philippe Soucaille, University of Toulouse |
| 9:15-9:40 AM | Expression Optimization of Multi-Enzyme Pathways for Xylose Utilization and Chemical Production- John Dueber, UC Berkeley |
| 9:40-10:05 AM | Invited Speaker: Protein Engineering of Isoprene Synthase Enables High Titer Isoprene Production- Maggie Cervin, DuPont |
| 10:05-10:30AM | Break |
| 10:30AM-12:35 PM | Session 2: Pathway Scale Engineering |
| Session Chairs: Michelle Chang, UC Berkeley, George Chen, Tsinghua University and John Dueber, UC Berkeley | |
| 10:30-10:55 AM | Invited Speaker: Engineering Organisms and Processes for Cost-Effective Lipid Production- Greg Stephanopoulos, MIT |
| 10:55-11:20 AM | Zach Serber, Zymergen |
| 11:20-11:45 AM | Invited Speaker: Rewriting Pathways to Life for Carbon Conservation- Jim Liao, UCLA |
| 11:45 AM - 12:10 PM | Engineering Static and Dynamic Tuning of Malonyl-CoA Derived Metabolite Biosynthesis in Microorganisms- Mattheos Koffas, RPI |
| 12:10-12:35 PM | Invited Speaker: Novel Biosynthetic Pathways for Production of Acids and Alcohols- Kristala Jones Prather, MIT |
| 12:35-2:00 PM | Lunch |
| 2:00-4:05 PM | Session 3: Genome Scale Engineering |
| Session Chairs: Hal Alper, University of Texas at Austin and Zach Serber, Zymergen | |
| 2:00-2:25 PM | Invited Speaker: Comprehensive characterization of genotype to phenotype relationships in E.coli- Morten Sommer, Technical University of Denmark |
| 2:25-2:50 PM | Metabolic Engineering via RNAi-Assisted Genome Evolution (RAGE)- Huimin Zhao, University of Illinois |
| 2:50-3:15 PM | Genetically Encoded Biosensors + FACS + Recombineering: Versatile Tools for Strain and Enzyme Development- Michael Bott, Forschungzentrum Juelich |
| 3:15-3:40 PM | A Unique Bioengineering Platform for the Efficient Optimization of Metabolic Pathways- Kedar Patel, DNA2.0 Inc. |
| 3:40-4:05 PM | Flux Response of Glycolysis and Storage Metabolism during Rapid Feast/Famine Conditions in Penicillium Chrysogenum Using Dynamic 13C Labeling- S. Ajoscha Wahl, DUT, Kluyver Netherlands |
| 4:00-4:45 PM | Free Time |
| 4:45-5:30 PM | Rapid Fire Poster Session (Poster Group 1) |
| 5:30-6:30 PM | Poster Session (Poster Group 1) |
| Session Chairs: Irina Borodina, Novo Nordisk Biosustainability Center,Michael Jewett, Northwester University, Julius Lucks, Cornell University, Caroline Peres, DuPont | |
| 6:30-7:00 PM | Buses to Yaletown |
| 6:45-8:00 PM | Reception at Earls in Yaletown |
Tuesday, June 17 |
|
| 7:00 AM-12:00 PM | Registration |
| 7:30-8:00 AM | Breakfast |
| 8:00-10:05AM | Session 4: Systems Biology and Engineering |
| Session Chairs: Iman Famili, Intrexon, Hiroshi Shimizu, Osaka University and Jamey Young, Vanderbilt University | |
| 8:00-8:25 AM | Invited Speaker: Systems Metabolic Engineering of Microorganisms for the Production of Polymers and Monomers- Sang Yup Lee, KAIST |
| 8:25-8:50 AM | Advances in 13C Metabolic Flux Analysis: Complete-MFA, Co-Culture MFA and Dynamic MFA- Maciek Antoniewicz, University of Delaware |
| 8:50-9:15 AM | Invited Speaker: Integrating Kintetic Models of Metabolism with k-OptForce for Strain Design- Costas Maranas, Penn State University |
| 9:15-9:40 AM | Design of Terpenoid Producing Synthetic Microbial Cell Factories by Integrative in silico Modeling and "-Omics" Data Analysis- Dong-Yup Lee, National University of Singapore |
| 9:40-10:05 AM | Invited Speaker: Opening Pandora's Box- Lars Nielsen, Australian Institute for Bioengineering & Nanotechnology |
| 10:05-10:30 AM | Break |
| 10:30 AM-12:35 PM | Session 5: Computational Methods and Design |
| Session Chairs: Anthony Burgard, Genomatica and Costas Maranas, Penn State University | |
| 10:30-10:55 AM | Invited Speaker: Integration of in silico Design and Experimental Evaluation for Creation of Microbial Cell Factories- Hiroshi Shimizu, Osaka University |
| 10:55-11:20 AM | Fast Enumeration of Smallest Metabolic Engineering Strategies in Genome-Scale Networks- Steffen Klamt, Max Planck Institute |
| 11:20-11:45 AM | Mapping Photoautotrophic Carbon Metabolism Using the INCA 13C Flux Analysis Platform- Jamey Young, Vanderbilt University |
| 11:45 AM - 12:10 PM | An Integrated Multi-Omics and Computational Characterization of Seven Unique Escherichia coli Production Chassis Commonly-Used in Industrial Biotechnology- Adam Feist, UC San Diego/Technical University of Denmark |
| 12:10-12:35 PM | Invited Speaker: Cyborg, Cloud Platform for Integrating Diverse Domains of Science- Deepak Chandran, Autodesk |
| 12:35-2:00PM | Lunch |
| 2:00-4:00 PM | Session 6: Rational Design-Build-Test Era |
| Session Chairs: Maciek Antoniewicz, University of Delaware, Akihiko Kondo, Kobe University and Michael Lynch, Duke University | |
| 2:00-2:30 PM | Invited Speaker: Using Systems Biology for Identification of Novel Metabolic Engineering Targets - Jens Nielsen, Chalmers University of Technology |
| 2:30-3:00 PM | Invited Speaker: Chris Voigt, MIT |
| 3:00-3:30 PM | Invited Speaker: Programming Biological Operating Systems: Genome Design, Assembly and Activation- Daniel Gibson, J. Craig Venter Institute and Synethtic Genomics, Inc. |
| 3:30-4:00 PM | Reducing the Complexity of Rational Microbial Design- Michael Lynch, Duke University |
| 4:00-4:45 PM | Free Time |
| 4:45-5:30 PM | Rapid Fire Poster Session (Poster Group 2) |
| 5:30-6:30 PM | Reception and Poster Session (Poster Group 2) |
Wednesday, June 18 |
|
| 7:00 AM-12:00 PM | Registration |
| 7:30-8:00 AM | Breakfast |
| 8:00-10:05 AM | Session 7: Industrial Applications Related to Chemicals and Fuels |
| Session Chairs: Ramon Gonzalez, Rice University and Kristala Jones Prather, MIT | |
| 8:00-8:25 AM | Metabolic Engineering of Yarrowia lipolytica to Produce High Value Products- Quinn Zhu, DuPont |
| 8:25-8:50 AM | Harnessing Metabolism for Sustainable Production of Chemicals: From Systems Biology to Commercial Scale- Mark Burk, Genomatica |
| 8:50-9:15 AM | Designing Microorganisms for Production of Diverse Biopolymers- George Chen, Tsinghua University |
| 9:15-9:40 AM | Design of Microbial Cell Factories for Lignocellulosic Biorefinery- Akihiko Kondo, Kobe University |
| 9:40-10:05 AM | Invited Speaker: Metabolic Engineering of Complex Natural Product Pathways in Bacteria- Ajikumar Parayil, Manus Biosciences |
| 10:05-10:30 AM | Break |
| 10:30 AM-12:35 PM | Session 8: Metabolic Engineering Applications to Impact Health |
| Session Chairs: Christian Metallo, UC San Diego and Nicola Zamboni, ETH | |
| 10:30-10:55 AM | Invited Speaker: Prosthetic Networks – Synthetic Biology-Inspired Treatment Strategies For Metabolic Disorders- Martin Fussenegger, ETH |
| 10:55-11:20 AM | Ovarian Cancer Metabolism: Systems-Scale Dynamics as a Platform for Identifying Therapeutic Targets- Mark Styczynski, Georgia Tech |
| 11:20-11:45 AM | Invited Speaker: Metabolic Strategies to Enhance the Toxicity of Nitric Oxide in Pathogens- Mark Brynildsen, Princeton University |
| 11:45 AM - 12:10 PM | Prediction and Quantification of Bioactive Microbiota Metabolites in Murine Gut- Kyongbum Lee, Tufts University |
| 12:10- 12:35 PM | Invited Speaker: The Gene Regulatory Network of Mycobacterium tuberculosis, v1.0- David Sherman, Seattle Biomed |
| 12:35-2:00 PM | Lunch |
| 2:00-4:05 PM | Session 9: Emerging Technologies |
| Session Chairs: Emily Leproust, Twist Biosciences | |
| 2:00-2:25 PM | Invited Speaker: Expression of Heterologous Sigma Factors in Escherichia coli to Explore the Heterologous Genomic Space for Building, Stepwise, Complex, Multicomponent Phenotypes- Eleftherios 'Terry' Papoutsakis, University of Delaware |
| 2:25-2:50 PM | Robust Technology for Antibiotics-Free Contamination Resistance- A. Joe Shaw, Novogy |
| 2:50-3:15 PM | Invited Speaker: Establishing Cell-Free Metabolic Engineering for Pathway Debugging and the Production of Sustainable Chemicals- Michael Jewett, Northwestern University |
| 3:15-3:40 PM | High Throughput Screening of Antibody Secretion in CHO Cells Using Split-GFP and Droplet Microfluidics- Johan Rockberg, KTH-Royal Institute of Technology |
| 3:40-4:05 PM | Invited Speaker: Transforming Yeast from Moonshiners into Oil Barons: Lessons from the Industrialization of Metabolic Engineering- Sunil Chandran, Amyris |
| 4:05-5:00 PM | IMES General Assembly Meeting |
| 5:00-6:00 PM | Poster Session and Drinks (Poster Group 2) |
| 6:00-7:00 PM | Awards Presentation and Lecture |
| 7:00-9:00 PM | Dinner |
Thursday, June 19 |
|
| 7:15-8:30 AM | Registration |
| 7:30-8:00 AM | Breakfast |
| 8:00-11:00 AM | Workshop- Tools for Commercial Bioprocess Design and Economic Analysis |
| 8:00-8:05 AM | Introduction- Jeff Lievense, Genomatica |
| 8:05-8:40 AM | Reverse the Direction in Bioprocess Development: From Full Scale to Synthetic Biology- Sef Heijnen, TU Delft |
| 8:40-9:40 AM | Economic Analysis of Fermentation Processes (Feedstock, Capital, Production Costs) - Jeff Lievense and Alex Patist, Genomatica |
| 9:40-9:50 AM | Break |
| 9:50-10:10 AM | Engineering Cost Model - Alex Patist |
| 10:10-10:40 AM | Case Studies (3-hydroxypropionic acid, undecanoic acid) - Jeff Lievense and Alex Patist |
| 10:40-10:55 AM | Process Omics: Chemical Advantage Dashboard - Jeff Lievense |
| 10:55-11:00 AM | Closing Remarks - Alex Patist |
